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Pain Management

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The prevalence of chronic pain in the United States is extremely high.  Approximately 100 million adults, representing 33% of the population, suffer daily with this diagnosis. The mechanisms of chronic pain are complex and multi-factorial. The three broad categories of pain include peripheral (nociceptive), neuropathic and non-nociceptive (peripheral) and may be related to a variety of clinical conditions including arthritis, fibromyalgia, diabetes, migraine and cancer. Pain is also influenced by a number of other factors including those that are psychological, social and environmental.

There are a variety of pharmacologic and non-pharmacologic approaches to managing chronic pain. Opioids, particularly the extended-release (ER) and long-acting (LA) preparations are among the most commonly used medications. While they are effective pain relievers, there are also a number of significant risks that must be taken into consideration when prescribing ER and LA opioids. Clinicians often face challenges in defining the most appropriate analgesic regimen for their individual patients.

In 2012, U.S. Food and Drug Administration (FDA) determined that a Risk Evaluation and Mitigation Strategy  (REMS) are necessary... (continue reading)

Pri-Med, in collaboration with American College of Physicians, has received commercial support for this community resource center provided by an educational grant from the REMS Program Companies. This educational activity is supported by an independent educational grant from the ER/LA Opioid Analgesic REMS Program Companies (RPC).  Please see www.er-la-opioidREMS.com for a listing of the member companies.

This activity is intended to be fully-compliant with the ER/LA Opioid Analgesics REMS education requirements issued by the U.S. Food & Drug Administration (FDA). 


The six CME activities, available here, are REMS-compliant training programs which focus on the safe prescribing of ER/LA opioid analgesics.


Clinical Resources
Format Content Category Date
Case on Treating Chronic Neuropathic Pain with Opioid Therapy Content Practice Management 06/07/2013
Case on Treating Chronic Pain in An Elderly Patient Content Practice Management 06/07/2013
Case on Avoiding Adverse Outcomes Associated with Opioid Treatment for Chronic Pain Content Practice Management 06/07/2013
Extended-Release Opioids for Severe Chronic Pain: A Point-Counterpoint Debate PDF Speaker-Led Content 08/13/2014
Activity Name Status
Complete the 6 modules to receive your SAFE Opioid Prescribing Certification
Module I: Evaluation is E...
Module II: Best Practices...
Module III: Evidence-Base...
Module IV: Talk to Me: Pr...
Module V: Everything You ...
Module VI: Getting the Mo...


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