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  • Wednesday, August 01, 2012
    Monthly Briefing
    July 2012 Briefing - OBGYN &: Women's Health



    Here are what the editors at HealthDay consider to be the most important developments in OBGYN & Women's Health for July 2012. This roundup includes the latest research news from journal articles, as well as the FDA approvals and regulatory changes that are the most likely to affect clinical practice.

    Levels of Etonogestrel Lower in Obese Women After Implant

    TUESDAY, July 31 (HealthDay News) -- Obese women who receive a contraceptive implant have lower drug levels in the six months following implant insertion compared with normal-weight women, according to a study published in the August issue of the American Journal of Obstetrics & Gynecology.

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    No Link Between Telomere Length and Diabetes Risk

    TUESDAY, July 31 (HealthDay News) -- Leukocyte telomere length is not independently associated with type 2 diabetes risk in postmenopausal women, according to a study published online July 24 in Diabetes.

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    Pelvic Floor Exercises Help With Incontinence in Late Pregnancy

    TUESDAY, July 31 (HealthDay News) -- A 12-week exercise program, including pelvic floor muscle training (PFMT), during pregnancy can help prevent and treat urinary incontinence in late pregnancy, according to research published online July 17 in BJOG: An International Journal of Obstetrics and Gynaecology.

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    Baseline HPV Test Predicts Cervical Cancer in Long Term

    MONDAY, July 30 (HealthDay News) -- Over 18 years of follow-up, baseline testing showing a negative result for human papillomavirus (HPV) DNA provides greater reassurance against invasive cervical cancer (CIN3+) than baseline normal Papanicolaou (Pap) testing, according to a study published online July 30 in the Journal of Clinical Oncology.

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    Women With Diabetes Report Low Sexual Satisfaction

    MONDAY, July 30 (HealthDay News) -- Women with diabetes are more likely than those without diabetes to report low overall sexual satisfaction, with insulin-treated women at higher risk for problems such as lubrication and orgasm, according to a study published in the August issue of Obstetrics & Gynecology.

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    Lymphovascular Invasion Is Independent Predictor of Survival

    FRIDAY, July 27 (HealthDay News) -- In patients with invasive breast cancer, lymphovascular invasion (LVI) is a strong and independent predictor of both breast cancer-specific survival (BCSS) and distant metastasis-free survival (DMFS), according to a study published in the Aug. 1 issue of Cancer.

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    Oral Contraceptives Typically Have Little Impact on Libido

    FRIDAY, July 27 (HealthDay News) -- For most women, oral contraceptives do not affect libido, but health care providers should be aware that some women may experience negative effects on sexual function, according to a study published online July 12 in The Journal of Sexual Medicine.

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    Low-Dose Duloxetine Deemed Safe for Urinary Incontinence

    FRIDAY, July 27 (HealthDay News) -- Duloxetine appears safe for the routine clinical care of women with stress urinary incontinence (SUI), according to a study published online July 23 in the British Journal of Clinical Pharmacology.

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    Racial Disparity in Diabetes Mostly Due to Lifestyle

    FRIDAY, July 27 (HealthDay News) -- For postmenopausal women there are large racial/ethnic differences in diabetes incidence, but these are mostly attributable to lifestyle factors, according to a study published online July 25 in Diabetes Care.

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    Excess Maternal Iodine Linked to Congenital Hypothyroidism

    THURSDAY, July 26 (HealthDay News) -- Excess maternal iodine supplementation can result in congenital hypothyroidism, according to a study published online July 26 in The Journal of Pediatrics.

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    Female Athletes Have Shorter Season Time to Injury

    THURSDAY, July 26 (HealthDay News) -- Female varsity athletes have a significantly shorter time to injury than males, regardless of sport or preseason fitness, according to a study published online July 23 in the Sports Medicine, Arthroscopy, Rehabilitation, Therapy & Technology.

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    Breast Cancer Doesn't Affect Sexual Function in Women

    THURSDAY, July 26 (HealthDay News) -- Sexual function does not seem to be significantly disrupted in women with a diagnosis of ductal carcinoma in situ (DCIS), according to a study published online July 19 in The Journal of Sexual Medicine.

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    CDC: HIV-Risk Behaviors Stable for U.S. High School Students

    TUESDAY, July 24 (HealthDay News) -- Although there were reductions in HIV-related risk behavior among U.S high school students from 1991 to the early 2000s, behaviors have subsequently stabilized, according to research published in the June 24 early-release issue of the U.S. Centers for Disease Control and Prevention's Morbidity & Mortality Weekly Report to coincide with the International AIDS Conference, held from July 22 to 27 in Washington, D.C.

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    Effects of Heavy Alcohol Exposure During Pregnancy Evaluated

    TUESDAY, July 24 (HealthDay News) -- Binge drinking and total alcohol intake during pregnancy correlate with child abnormalities linked to alcohol exposure, according to a study published online July 23 in Alcoholism: Clinical & Experimental Research.

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    CDC: No Change in Proportion of Unintended Births in U.S.

    TUESDAY, July 24 (HealthDay News) -- The proportion of unintended births in the United States has remained unchanged from 1982, and was about 37 percent in 2006 to 2010, according to a report issued July 24 by the U.S. Centers for Disease Control and Prevention's National Center for Health Statistics (NCHS).

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    Role of Annual Well-Woman Assessment Reviewed

    TUESDAY, July 24 (HealthDay News) -- For women, an annual assessment is an important part of medical care and should include screening, evaluation, and counseling, according to a Committee Opinion published online July 23 in Obstetrics & Gynecology.

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    Modest Prediction of Preterm Birth Using Clinical Features

    MONDAY, July 23 (HealthDay News) -- For healthy nulliparous women, the ability to predict spontaneous preterm birth (SPTB) using clinical characteristics is modest, according to a study published online July 16 in PLoS One.

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    Study Examines Effect of Trisomy 13, 18 on Families, Providers

    MONDAY, July 23 (HealthDay News) -- Parents of children with trisomy 13 and trisomy 18 (T13-18) who belong to social networks have positive experiences in spite of the difficulties, and report that their children enrich their family life, according to a study published online July 23 in Pediatrics.

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    Afinitor Approved for Advanced Breast Cancer

    FRIDAY, July 20 (HealthDay News) -- Afinitor (everolimus) has been approved in combination with the drug exemestane to treat postmenopausal women with advanced hormone-receptor positive, HER2-negative breast cancer, the U.S. Food and Drug Administration said Friday.

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    Adoption of New Screening Guidelines Ups GDM Diagnosis

    FRIDAY, July 20 (HealthDay News) -- Implementation of the International Association of Diabetes in Pregnancy Study Group (IADPSG) recommendations for gestational diabetes mellitus (GDM) screening in Israel would increase GDM diagnoses by approximately 50 percent, with risk stratification recommended to reduce over-treatment, according to research published online July 11 in Diabetes Care.

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    High-Strain, Active Jobs Up Cardio Disease Risk for Women

    FRIDAY, July 20 (HealthDay News) -- For women, high-strain and active jobs correlate with an increased long-term risk of cardiovascular disease (CVD), according to a study published online July 18 in PLoS One.

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    BMI Affects Aromatase Inhibitor-Linked Estrogen Suppression

    FRIDAY, July 20 (HealthDay News) -- Body mass index (BMI) affects the level of estradiol and estrone sulfate suppression achieved when treating postmenopausal women with estrogen receptor (ER)-positive breast cancer with either of two aromatase inhibitors, anastrozole or letrozole, according to a study published online July 16 in the Journal of Clinical Oncology.

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    Higher Phthalate Levels Linked to Diabetes Risk in Women

    THURSDAY, July 19 (HealthDay News) -- Urinary levels of several phthalates are associated with an increased odds of diabetes in women, according to a study published online July 13 in Environmental Health Perspectives.

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    Specific Paternal Occupations Linked to Risk of Birth Defects

    THURSDAY, July 19 (HealthDay News) -- Specific paternal occupations correlate with increased risk of birth defects, and maternal occupational exposure to certain solvents correlates with increased risk of congenital heart defects (CHDs), according to two studies published online July 17 in Occupational & Environmental Medicine.

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    Most Doctors Satisfied With Electronic Health Records

    THURSDAY, July 19 (HealthDay News) -- Although only 55 percent of physicians had adopted electronic health records (EHRs) in 2011, most are somewhat or very satisfied with their system and most report enhanced patient care, according to a July data brief issued by the U.S. Centers for Disease Control and Prevention's National Center for Health Statistics (NCHS).

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    ~12,000 Preventable Deaths in English Hospitals Annually

    THURSDAY, July 19 (HealthDay News) -- Approximately 12,000 hospital deaths in England each year are preventable, according to research published online July 7 in BMJ Quality & Safety.

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    Swedish Study Questions Value of Mammography Screening

    THURSDAY, July 19 (HealthDay News) -- County-specific mortality statistics from Sweden indicate little benefit of mammography screening on breast cancer mortality, according to a study published online July 17 in the Journal of the National Cancer Institute.

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    Poorer Patient Experience at Safety-Net Hospitals

    THURSDAY, July 19 (HealthDay News) -- Safety-net hospitals (SNHs) perform worse on nearly every measure of patient experience, according to a study published online July 16 in the Archives of Internal Medicine.

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    Another New Weight-Loss Drug Approved

    WEDNESDAY, July 18 (HealthDay News) -- Qsymia (phentermine and topiramate extended-release) has been approved by the U.S. Food and Drug Administration, making it the second weight-loss drug to be given the agency's green light in less than a month.

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    Physical Inactivity Accounts for Considerable Disease Burden

    WEDNESDAY, July 18 (HealthDay News) -- Physical inactivity has a considerable impact on the burden of major non-communicable diseases, and causes 9 percent of premature mortality worldwide, according to a study published online July 18 in The Lancet.

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    High Infant Birth Weight Ups Maternal Breast Cancer Risk

    WEDNESDAY, July 18 (HealthDay News) -- For women who give birth to large birth weight infants, there is an increased risk of breast cancer, even after adjustment for the mother's birth weight and traditional breast cancer risk factors, according to a study published online July 17 in PLoS One.

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    First Drug Approved to Lower Risk of Acquiring HIV

    TUESDAY, July 17 (HealthDay News) -- Truvada (emtricitabine/tenofovir disoproxil fumarate) is the first drug to be approved by the U.S. Food and Drug Administration to reduce the risk of contracting HIV among adults at higher risk of acquiring the AIDS-causing virus.

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    Social Network Analysis IDs Informal Physician Networks

    TUESDAY, July 17 (HealthDay News) -- Informal networks among physicians who share patients demonstrate substantial geographic variability, while within networks, physician and patient characteristics are similar, according to a study published in the July 18 issue of the Journal of the American Medical Association.

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    Urinary Incontinence Common in Never-Pregnant Women

    TUESDAY, July 17 (HealthDay News) -- Urinary incontinence (UI) is common in self-reports by young women who have never been pregnant, according to a study published in the July 17 issue of the Annals of Internal Medicine.

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    Physical Abuse Doubles Risk of Metabolic Syndrome in Women

    TUESDAY, July 17 (HealthDay News) -- After adjusting for age, ethnicity, and menopausal status, a history of childhood physical abuse more than doubles a woman's risk of developing metabolic syndrome during midlife, according to research published online July 9 in Health Psychology.

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    One in Five 19- to 64-Year-Old U.S. Women Uninsured in 2010

    MONDAY, July 16 (HealthDay News) -- In 2010, 20 percent of women aged 19 to 64 years were uninsured, with many more inadequately insured, according to a report published July 13 by the Commonwealth Fund.

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    Macromastia Has Substantial Negative Impact on Teens

    MONDAY, July 16 (HealthDay News) -- Adolescents with macromastia have reduced health-related quality of life, lower self-esteem, more breast-related symptoms, and are at higher risk for disordered eating, compared with their peers, according to a study published online July 16 in Pediatrics.

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    Dietary Self-Monitoring Linked to Greater Weight Loss

    MONDAY, July 16 (HealthDay News) -- Dietary self-monitoring in the form of food journal use correlates with improved weight loss, while missing meals and eating out frequently are associated with less weight loss among postmenopausal overweight-to-obese women, according to a study published online July 16 in the Journal of the Academy of Nutrition and Dietetics.

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    Maternal Obesity Linked to Impaired Fetal Iron Transfer

    FRIDAY, July 13 (HealthDay News) -- Maternal obesity is associated with impaired iron transfer to the fetus, possibly through upregulation of hepcidin, according to a study published online June 21 in the Journal of Perinatology.

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    Vaginal Dilation Outcomes Equivalent to Vaginoplasty

    FRIDAY, July 13 (HealthDay News) -- Long-term psychosexual outcomes for patients undergoing vaginal dilation are at least equivalent to those undergoing vaginoplasty, according to a study published in the July issue of The Journal of Sexual Medicine.

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    High Phobic Anxiety Linked to Relative Telomere Length

    FRIDAY, July 13 (HealthDay News) -- Older women who have phobic anxiety have shorter relative telomere lengths, according to a study published online July 11 in PLoS One.

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    One in Five Women Has Re-Op After Breast Cancer Surgery

    FRIDAY, July 13 (HealthDay News) -- Twenty percent of women who undergo breast conserving surgery in England undergo reoperation, which is significantly more likely for women with carcinoma in situ versus isolated invasive disease, according to a study published July 12 in BMJ.

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    Most Breast Cancer Patients Return to Working Same Hours

    THURSDAY, July 12 (HealthDay News) -- Nearly three-quarters of women treated for breast cancer return to their prediagnosis working time, according to a study published online July 9 in the Journal of Clinical Oncology.

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    Alcohol Intake Attenuates Bone Turnover After Menopause

    WEDNESDAY, July 11 (HealthDay News) -- For postmenopausal women, there are increased levels of markers of bone turnover with alcohol abstinence, while resumption of alcohol intake reduces levels of these markers, according to a study published online July 9 in Menopause.

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    Moderate Drinking Cuts Risk of Rheumatoid Arthritis in Women

    WEDNESDAY, July 11 (HealthDay News) -- Moderate alcohol consumption correlates with reduced incidence of rheumatoid arthritis (RA) among women, according to a study published online July 10 in BMJ.

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    Breastfeeding Linked to Lower BMI in Postmenopausal Women

    TUESDAY, July 10 (HealthDay News) -- Breastfeeding correlates with a small but significant reduction in body mass index (BMI) much later in life, according to a study published online July 10 in the International Journal of Obesity.

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    Flu Shot in Pregnancy Not Tied to Adverse Fetal Outcomes

    TUESDAY, July 10 (HealthDay News) -- Exposure to adjuvanted influenza A(H1N1)pdm09 vaccination during pregnancy does not increase the risk of adverse fetal outcomes, and influenza vaccination correlates with a small but significantly increased risk of Guillain-Barré Syndrome (GBS), according to two studies published in the July 11 issue of the Journal of the American Medical Association.

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    Top Medical Organizations Support Hormone Replacement

    MONDAY, July 9 (HealthDay News) -- Ten years after the Women's Health Initiative (WHI) declared that hormone replacement therapy may do more harm than good in the prevention of chronic disease, the North American Menopause Society (NAMS), the American Society for Reproductive Medicine, and The Endocrine Society have issued a joint statement concluding hormone therapy safe and effective in the treatment of menopausal symptoms.

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    Vitamin D Status Impacts Weight Gain in Older Women

    MONDAY, July 9 (HealthDay News) -- For older women who gain weight, high levels of 25-hydroxyvitamin D [25(OH)D] are linked with less weight gain compared to that found in women with low levels of 25(OH)D, according to a study published online June 25 in the Journal of Women's Health.

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    Unsuccessful Fertility Drug Use Lowers Breast Cancer Risk

    MONDAY, July 9 (HealthDay News) -- Women with unsuccessful use of fertility drugs are at a significantly reduced risk of young-onset breast cancer, according to a study published online July 6 in the Journal of the National Cancer Institute.

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    Evidence of Herd Immunity After Introduction of HPV Vaccine

    MONDAY, July 9 (HealthDay News) -- Following introduction of the human papillomavirus (HPV) vaccine there has been a significant decrease in the prevalence of vaccine-type HPV among vaccinated young women and evidence of herd protection in unvaccinated women, according to a study published online July 9 in Pediatrics.

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    Prenatal Caffeine Intake Not Linked to Children's Behavior

    MONDAY, July 9 (HealthDay News) -- Maternal prenatal caffeine intake is not associated with behavior problems in young children, according to a study published online July 9 in Pediatrics.

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    Similar Presentation for Bladder Outlet Obstructions

    MONDAY, July 9 (HealthDay News) -- Women with dysfunctional voiding (DV) and primary bladder neck obstruction (PBNO) have similar clinical presentation, with poorer emptying for those with PBNO, according to a study published in the July issue of Urology.

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    Gestational Diabetes Risk Up With Antipsychotic Use

    FRIDAY, July 6 (HealthDay News) -- Maternal use of antipsychotic drugs during pregnancy is linked to an increased risk of gestational diabetes, according to a study published in the July issue of the Archives of General Psychiatry.

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    Sentinel Node Biopsy Safe for Vulvar Squamous Cell Cancer

    FRIDAY, July 6 (HealthDay News) -- For women with squamous cell carcinoma (SCC) of the vulva, sentinel lymph node (SLN) biopsy may be safely used in place of inguinal femoral lymphadenectomy, according to research published online July 2 in the Journal of Clinical Oncology.

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    Self-Directed Violence, Suicide Up in Parasite-Infected Women

    FRIDAY, July 6 (HealthDay News) -- Women infected with the common parasite Toxoplasma gondii (T. gondii) have an increased risk of self-directed violence, violent suicide attempts, and suicide, according to research published online July 2 in the Archives of General Psychiatry.

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    CDC: Chagas Disease May Be Overlooked in Newborns

    THURSDAY, July 5 (HealthDay News) -- Chagas disease, a parasitic infection that can lead to cardiomyopathy, is usually transmitted by contact with triatomine insects, but it can be passed congenitally, according to a case report published in the July 6 issue of the U.S. Centers for Disease Control and Prevention's Morbidity & Mortality Weekly Report.

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    High-Dose Vitamin D 'Somewhat Favorable' in Fracture Prevention

    THURSDAY, July 5 (HealthDay News) -- High-dose (≥800 IU daily) vitamin D supplementation is associated with a decreased risk of hip fracture and nonvertebral fractures among older adults, according to a study published in the July 5 issue of the New England Journal of Medicine.

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    First Over-the-Counter HIV Test Approved

    TUESDAY, July 3 (HealthDay News) -- The first over-the-counter test to detect antibodies to the virus that causes AIDS has been approved by the U.S. Food and Drug Administration, the agency said Tuesday.

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    Ovarian Grafts Restore Endocrine Function Long Term

    TUESDAY, July 3 (HealthDay News) -- For female cancer survivors, heterotopic transplantation of cryobanked human ovarian tissue results in restoration of endocrine function within a few months that can last for as long as seven years, according to a study published in the June issue of the Journal of Assisted Reproduction and Genetics.

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    Rheumatoid Arthritis Drug Not Linked to Specific Birth Defects

    TUESDAY, July 3 (HealthDay News) -- The rheumatoid arthritis drug leflunomide is not a major cause of birth defects in women who inadvertently become pregnant while taking the drug, although pregnancy should be avoided, according to a study in the July issue of Arthritis & Rheumatism.

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    Risk of Stillbirth Up at Extremes of Birth Weight

    MONDAY, July 2 (HealthDay News) -- The risk of stillbirth is increased at extreme percentiles of birth weight across all gestational ages, according to a study published online May 17 in the Journal of Perinatology.

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    Childhood Physical Discipline Linked to Mental Health Issues

    MONDAY, July 2 (HealthDay News) -- A significant percentage of mood, anxiety, and personality disorders and substance abuse in U.S. adults can be attributed to harsh physical punishment during childhood, according to research published online July 2 in Pediatrics.

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