Byron L. Cryer, MD, is Professor of Medicine in the Division of Digestive and Liver Diseases and an Associate Dean at the University of Texas Southwestern Medical Center at Dallas and the North Texas VA Health Care System. He graduated from Harvard University and received his medical degree from Baylor College of Medicine in 1986, where he also completed his internal medicine residency training. Dr. Cryer completed his gastroenterology fellowship training at the University of Texas Southwestern Medical Center in 1992. He is active in the gastroenterology professional associations and was an associate chairman of the Esophagus, Stomach, and Duodenum section of the American Gastroenterological Association. His clinical interests are in general gastroenterology. Dr. Cryer's specific areas of interest are acid-peptic diseases of the upper gastrointestinal tract. His primary research interest has been in the pathogenesis of peptic ulcer disease. His research focus has been clinically oriented in that he has exclusively studied the pathophysiology of these processes in humans. Dr. Cryer has distinguished himself as an internationally recognized clinical investigator and thought leader in the field of the gastrointestinal adverse effects of medications. Most of this focus has been to study the gastrointestinal consequences effects of aspirin and the non-steroidal anti-inflammatory drugs (NSAIDS). Among the contributions which Dr. Cryer has made to the area of medication-induced gastrointestinal disease, his most important recent contributions have been in the evaluation of COX-2 specific inhibitors as a strategy to improve the gastrointestinal safety of NSAIDS. Additionally, has regulatory experience having served a five year term as a member, U.S. Food and Drug Administration (FDA) Advisory Committee for Gastrointestinal Drugs and as a Special Government Consultant to Center for Drug Evaluation Research Gastrointestinal Drugs, ad hoc.