In this webcast, Drs. Marc Riedl and Michael Manning instruct primary care providers on how to differentially diagnose hereditary angioedema (HAE), a potentially fatal swelling condition, from other more common forms of angioedema. They also review current guidelines for the management of HAE, including therapies for both treatment of acute attacks and long-term prophylaxis.

Learning Objectives

  • Describe the epidemiology, pathophysiology, and burden of illness of hereditary angioedema (HAE)
  • Recognize HAE as a possible cause of recurrent angioedema and formulate an appropriate diagnostic workup for various types of HAE (Type I, Type II, and normal C1-INH)
  • Utilize individualized HAE treatment strategies, taking into consideration risks and benefits of therapies, disease characteristics and severity, comorbid conditions, patient quality of life, and patient preference

Faculty Disclosures

Michael E. Manning, MD, FAAAAI

Medical Advisory Board for Shire. Contracted Research from CSL Behring; Dyax Corporation; Genentech; Merck & Co., Inc.; and Shire. Speakers Bureau for CSL Behring; Dyax Corporation; and Shire.

Marc A. Riedl, MD, MS

Speakers Bureau for CSL Behring; Dyax Corporation; Salix; and Shire. Contracted Research from BioCryst Pharmaceuticcals, Inc.; CSL Behring; Dyax Corporation; Pharming Group; and Shire. Consultant for BioCryst Pharmaceuticcals, Inc.; CSL Behring; Dyax Corporation; Isis Pharmaceuticals, Inc.; Salix; and Shire.


Non-faculty contributors and others involved in the planning, development, and editing/review of the content have no relevant financial relationships to disclose.

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