This program is designed to teach primary care providers how to diagnose and determine underlying causes of chronic urticaria (CU) and how to utilize current, evidence-based treatment recommendations for antihistamine-resistant cases of CU.

Learning Objective

  • Formulate an appropriate diagnostic workup for symptomatology suggestive of chronic urticaria taking into account the potential differential diagnosis.
  • Incorporate into practice evidence-based treatment options and guidelines for managing chronic urticaria that maximize efficacy, minimize adverse effects, and take into account patient quality of life.

Faculty Disclosure

Luz Fonacier, MD, FAAAAI

Speakers Bureau for Baxter International Inc. Contracted Research for Baxter International Inc.; Genentech; and Merck & Co., Inc.

Michael E. Manning, MD, FAAAAI

Medical Advisory Board for Shire. Contracted Research from CSL Behring; Dyax Corporation; Genentech; Merck & Co., Inc.; and Shire. Speakers Bureau for CSL Behring; Dyax Corporation; and Shire.


Non-faculty contributors and others involved in the planning, development, and editing/review of the content have no relevant financial relationships to disclose.

Commercial Supporters

Genentech and Novartis Pharmaceuticals Corporation

Education Partner


Fine Print

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The opinions, ideas, and recommendations expressed in this educational activity are those of the faculty only and are not necessarily endorsed by, nor do they necessarily reflect, those of their affiliated institutions, pmiCME, pmiCME Advisory Boards and Consultants, DBC Pri-Med, LLC.

Clinical judgment must guide each clinician in weighing the possible risks, benefits, or contraindications of any diagnostics, interventions or treatments discussed. Clinicians should review manufacturers’ product information and consider these with the recommendations of other authorities when applying the assessment and/or clinical management strategies discussed in this activity to the care of their patients.

pmiCME educational activities are developed and conducted in accordance with the ACCME's Essential Areas and Policies. It is the mission of pmiCME to develop and present educational activities that are timely, fair-balanced, scientifically rigorous, and that serve to improve patient outcomes. To that end, we welcome your comments about how to better serve your needs.

pmiCME Accredited Provider
Pri-Med programs are owned and operated by DBC Pri-Med, LLC, a division of Diversified Communications, Inc. pmiCME, the accredited division of Pri-Med, is accredited with commendation by the ACCME and approved as a provider of continuing education by the AANP. pmiCME is the accredited provider for this activity.

Disclosures and Conflict of Interest
pmiCME requires all individuals in a position to influence educational content for pmiCME-certified CME activities to disclose relevant personal financial relationships with commercial interests prior to contributing to its educational activities. pmiCME assesses disclosed relationships and follows a defined process to resolve real or implied conflicts to ensure, to the best of its ability, that all educational content is free of commercial bias. Financial disclosures are listed in the activity syllabus and will also be printed on the slides and announced at the start of each presentation.

Discussion of Off-Label Uses and Investigational Products
During the course of their presentations, the faculty may mention uses of products that have not been approved in the United States for the indication(s) being discussed. All presenters are instructed to notify participants when they are discussing unapproved uses or investigational agents. In addition, specific slides will include notation of the off-label use or investigational agent being discussed. Views presented related to unapproved uses of products are solely those of the presenter(s) and are not endorsed by pmiCME or DBC Pri-Med, LLC.

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