Reuters Health News

• Ofatumumab promising in refractory follicular lymphoma (07/22/2008)
  By David Douglas
  NEW YORK (Reuters Health) - The human monoclonal antibody ofatumumab was well tolerated by patients with relapsed or refractory follicular...
• Most foreign-born TB patients in US from sub-Saharan Africa, SE Asia (07/22/2008)
  NEW YORK (Reuters Health) - Between 2001-2006, 53% of the tuberculosis cases that occurred among foreign-born individuals in the US involved persons...
• Low mass islet cell transplants achieve insulin independence (07/22/2008)
  NEW YORK (Reuters Health) - Allogeneic islet cell transplantation outcome is improved with smaller transplant size and with addition of etanercept...

Anemia

• Endogenous erythropoietin tied to outcome in anemic heart patients (07/17/2008)
  By David Douglas
  NEW YORK (Reuters Health) - The ratio of actual to predicted endogenous erythropoietin levels casts light on the risk of mortality in chronic heart...
• Intermittent malaria chemoprevention improves children's cognitive function (07/10/2008)
  NEW YORK (Reuters Health) - Results of a large field trial in Kenya indicate that a school-based program of intermittent preventive treatment of...
• Pregnancy a risk factor for acute MI (07/07/2008)
  NEW YORK (Reuters Health) - Pregnancy increases the risk of acute myocardial infarction (MI) 3- to 4-fold, according to a literature review published...
• Mortality in severe malaria increases with age (07/03/2008)
  By C. Vidya Shankar, MD
  CHENNAI, India - (Reuters Health) - Mortality in severe falciparum malaria is significantly greater among adults over 50 years of age than in other...

Arrhythmias

• Red blood cell fatty acid profile is altered in heart failure patients (07/09/2008)
  By Michelle Rizzo
  NEW YORK (Reuters Health) - Omega- 3 supplementation may not be prudent in patients with left ventricular dysfunction, based on findings published in...
• Cardiomyopathy not improved by intramyocardial skeletal myoblast injections (07/08/2008)
  By Will Boggs, MD
  NEW YORK (Reuters Health) - Intramyocardial injections of skeletal myoblasts in patients with ischemic cardiomyopathy does not improve ventricular...
• Diabetic ketoacidosis prolongs QT interval in children (06/26/2008)
  By David Douglas
  NEW YORK (Reuters Health) - During diabetic ketoacidosis in children, the QT interval corrected for heart rate (QTc) is often elevated, researchers...

Asthma

• Female gender and smoke exposure predict asthma response to montelukast (07/18/2008)
  NEW YORK (Reuters Health) - In children with asthma treated with inhaled corticosteroids and requiring rescue medication, responsiveness to the...
• Furosemide inhalation can alleviate dyspnea in COPD (07/18/2008)
  NEW YORK (Reuters Health) - Inhalation of furosemide relieves exertional dyspnea in some patients with chronic obstructive pulmonary disease (COPD),...
• Regular salmeterol use for asthma ups risk of serious adverse events (07/17/2008)
  NEW YORK (Reuters Health) - Patients with chronic asthma who use the long-acting beta-2 agonist salmeterol on a daily basis are at increased risk for...
• U.S. still flunks healthcare test, group says (07/17/2008)
  By Maggie Fox, Health and Science Editor
  WASHINGTON (Reuters) - The United States fails on most measures of health care quality, with Americans waiting longer to see doctors and more likely...
• Eradicating nasal S. aureus does not improve allergic rhinitis (07/16/2008)
  By David Douglas
  NEW YORK (Reuters Health) - Topical nasal mupirocin is an effective means of eradicating Staphylococcus aureus nasal colonization in patients with...
• Etanercept improves outcomes somewhat in corticosteroid-refractory asthma (07/15/2008)
  NEW YORK (Reuters Health) - Tumor necrosis factor (TNF) blockade with etanercept produces a small improvement in asthma control and systemic...
• Mortality from complicated peptic ulcer high in COPD patients (07/15/2008)
  NEW YORK (Reuters Health) - Chronic obstructive pulmonary disease is associated with substantially increased short-term mortality among patients with...
• Triple therapy superior for treating moderate to severe COPD (07/14/2008)
  By Will Boggs, MD
  NEW YORK (Reuters Health) - Triple therapy with salmeterol/fluticasone and tiotropium is superior to the individual components for patients with...
• Oximetry with capnography defines oxygen therapy needs (07/11/2008)
  NEW YORK (Reuters Health) - Combined oximetry and cutaneous capnography is an effective and non-invasive means of oxygen titration in patients...
• One epinephrine dose may not suffice for children with multiple food allergies (07/09/2008)
  NEW YORK (Reuters Health) - Nearly one in five food-induced anaphylactic reactions that occur in children with multiple food allergies will require...
• Inflammatory processes may link asthma and rhinosinusitis (06/26/2008)
  NEW YORK (Reuters Health) - A study in asthmatic patients published in the June issue of Mayo Clinic Proceedings suggests a direct relationship among...

Autism

• U.S. measles outbreak hits 127 people in 15 states (07/10/2008)
  By Will Dunham
  WASHINGTON (Reuters) - The biggest U.S. outbreak of measles since 1997 has affected 127 people in 15 states, most of whom were not vaccinated,...
• Autism risk with low birth weight, prematurity higher for girls (06/27/2008)
  By Anne Harding
  NEW YORK (Reuters Health) - Low birth weight and preterm delivery increase the likelihood that a child will be autistic, with girls being at...

Blood Disorders

• Endogenous erythropoietin tied to outcome in anemic heart patients (07/17/2008)
  By David Douglas
  NEW YORK (Reuters Health) - The ratio of actual to predicted endogenous erythropoietin levels casts light on the risk of mortality in chronic heart...
• Intermittent malaria chemoprevention improves children's cognitive function (07/10/2008)
  NEW YORK (Reuters Health) - Results of a large field trial in Kenya indicate that a school-based program of intermittent preventive treatment of...
• Pregnancy a risk factor for acute MI (07/07/2008)
  NEW YORK (Reuters Health) - Pregnancy increases the risk of acute myocardial infarction (MI) 3- to 4-fold, according to a literature review published...
• Mortality in severe malaria increases with age (07/03/2008)
  By C. Vidya Shankar, MD
  CHENNAI, India - (Reuters Health) - Mortality in severe falciparum malaria is significantly greater among adults over 50 years of age than in other...

Breast Cancer

• Electrothermal vessel sealing effective during mastectomy (07/18/2008)
  By David Douglas
  NEW YORK (Reuters Health) - An electrothermal bipolar vessel sealing system (LigaSure Precise, Valleylab) reduces operative time and appears to be...
• Breast self-examination does not cut breast cancer mortality (07/16/2008)
  NEW YORK (Reuters Health) - An analysis of data from two large population-based studies suggests that regular breast self-examination does not reduce...
• Lapatinib appears safe in patients with breast cancer (07/14/2008)
  NEW YORK (Reuters Health) - Pooled data from 44 studies indicate that the tyrosine kinase EGFR and HER2 inhibitor lapatinib exhibits low...
• Lapatinib promising for advanced ErbB2-amplified breast cancer (07/08/2008)
  NEW YORK (Reuters Health) - In a phase II trial, the investigational agent lapatinib was well tolerated and showed clinical activity as first-line...
• Drop in US cancer death rates seen mainly in highly educated individuals (07/08/2008)
  NEW YORK (Reuters Health) - From 1993 to 2001, death rates from common cancers fell in the United States, but this decline was primarily confined to...
• CK19 mRNA expression identifies lymph node metastases intraoperatively (07/08/2008)
  NEW YORK (Reuters Health) - Measurement of CK19 mRNA expression intraoperatively can be used as a rapid diagnostic method to detect lymph node...
• Treatment delays common in men with breast cancer (07/07/2008)
  By Megan Rauscher
  NEW YORK (Reuters Health) - Male breast cancer is often diagnosed at an advanced stage and axillary lymph node involvement is frequently seen at...
• HER-2 improves survival in patients with breast cancer brain metastasis (07/01/2008)
  By David Douglas
  NEW YORK (Reuters Health) - HER-2 status is a strong predictor of survival in patients with brain metastases from breast cancer, according to...
• Investigational drug combination plus chemotherapy promising in breast cancer cell lines (07/01/2008)
  By Martha Kerr
  NEW YORK (Reuters Health) - A chemotherapy regimen targeting both p53 mutations and tumor vasculature "has complementary and potent antitumor...
• Metastatic potential may be inherent in DCIS cells (06/30/2008)
  By Martha Kerr
  NEW YORK (Reuters Health) - Ductal carcinoma in situ (DCIS) cells may be able to invade, and perhaps metastasize, from the outset rather than being...
• Molecular breast imaging more cost-effective than MRI without loss of sensitivity (06/30/2008)
  By Martha Kerr
  NEW YORK (Reuters Health) - Research presented at the Department of Defense's annual Era of Hope breast cancer meeting indicates that molecular...
• Breast cancer cells traced to transplanted stem cells (06/26/2008)
  By Martha Kerr
  NEW YORK (Reuters Health) - Stem cells can give rise to both breast cancer cells and the cells of the tumor microenvironment. Furthermore, stem...
• Outreach program speeds breast cancer diagnosis in black women (06/23/2008)
  By Karla Gale
  NEW YORK (Reuters Health) - Implementation of breast cancer outreach initiatives in Atlanta, Georgia, doubled the proportion of stage 0 tumors...
• African American women face higher death risk from metastatic breast cancer (06/23/2008)
  By Will Boggs, MD
  NEW YORK (Reuters Health) - The higher death risk for African American women with metastatic breast cancer persists in clinical trials where overall...

Cancer

• U.S. FDA, CDC say Merck's Gardasil shot remains safe (07/22/2008)
  WASHINGTON (Reuters) - A review of health problems reported after women and girls received Merck & Co's Gardasil vaccine shows it remains safe...
• Endostatin levels reflect pancreatic cancer progression (07/22/2008)
  NEW YORK (Reuters Health) - Endostatin levels are increased in patients with pancreatic cancer and decline after surgical treatment or chemotherapy,...
• Shortened leukocyte telomeres linked with high mortality in CAD patients (07/21/2008)
  By Martha Kerr
  NEW YORK (Reuters Health) - Patients with stable coronary artery disease who exhibit short telomere length in leukocytes are at nearly double the...
• Electrothermal vessel sealing effective during mastectomy (07/18/2008)
  By David Douglas
  NEW YORK (Reuters Health) - An electrothermal bipolar vessel sealing system (LigaSure Precise, Valleylab) reduces operative time and appears to be...
• Zoledronic acid reduces fracture risk in cancer patients with bone metastases (07/18/2008)
  NEW YORK (Reuters Health) - The bisphosphonate zoledronic acid normalizes or maintains N-telopeptide of type 1 collagen (NTx) levels in cancer...
• Long-term tricyclic antidepressants linked to non-Hodgkin lymphoma (07/18/2008)
  NEW YORK (Reuters Health) - The results of a study published in the July issue of Epidemiology suggest that long-term users of tricyclic...
• Anal HPV infection common in heterosexual men (07/18/2008)
  By Anthony J. Brown, MD
  NEW YORK (Reuters Health) - Roughly one in four heterosexual men have anal human papillomavirus (HPV) infection and, in many cases, an oncogenic type...
• Limited benefit seen with docetaxel and rapid androgen cycling for prostate cancer (07/17/2008)
  NEW YORK (Reuters Health) - Because of a high incidence of neutropenia and little sustained response, docetaxel with rapid androgen cycling is not...
• Immune and clinical responses seen with glioblastoma vaccination (07/17/2008)
  NEW YORK (Reuters Health) - Findings from a new study provide the first evidence that the T-cell response seen after therapeutic vaccination for...
• Risk of ovarian cancer is not reduced with analgesic use (07/17/2008)
  NEW YORK (Reuters Health) - Regular use of analgesics does not appear to reduce the risk of ovarian cancer, according to findings published in the...
• Reverse transcriptase inhibitors promising against renal clear-cell carcinoma (07/16/2008)
  NEW YORK (Reuters Health) - The non-nucleoside reverse transcriptase (RT) inhibitors efavirenz and nevirapine induce cell differentiation and enhance...
• Talactoferrin promising against metastatic kidney cancer (07/16/2008)
  By Will Boggs, MD
  NEW YORK (Reuters Health) - Talactoferrin, a recombinant form of human lactoferrin, shows activity against metastatic renal cell carcinoma (RCC) in...
• Breast self-examination does not cut breast cancer mortality (07/16/2008)
  NEW YORK (Reuters Health) - An analysis of data from two large population-based studies suggests that regular breast self-examination does not reduce...
• Osteonecrosis uncommon in childhood cancer survivors (07/15/2008)
  NEW YORK (Reuters Health) - Although osteonecrosis is rare in adult survivors of childhood cancer, they appear to be at significantly increased risk...
• Conjunctiva carcinoma risk increased in HIV patients (07/14/2008)
  NEW YORK (Reuters Health) - Patients infected with HIV face an increased risk of developing squamous cell carcinoma of the conjunctiva (SCCC),...
• Lapatinib appears safe in patients with breast cancer (07/14/2008)
  NEW YORK (Reuters Health) - Pooled data from 44 studies indicate that the tyrosine kinase EGFR and HER2 inhibitor lapatinib exhibits low...
• Elevated C-reactive protein predicts poor outcome in prostate cancer (07/11/2008)
  NEW YORK (Reuters Health) - An elevated plasma C-reactive protein (CRP) concentration is associated with poor survival and a lower probability of...
• Vitamin D levels tied to colorectal cancer survival (07/11/2008)
  NEW YORK (Reuters Health) - Patients with colorectal cancer with higher plasma 25-hydroxyvitamin D3 (25(OH)D) levels before their diagnosis appear to...
• With mucositis, oral temperature reading may not reflect infection (07/11/2008)
  NEW YORK (Reuters Health) - Oral inflammation (i.e., mucositis) leads to an increase in local oral temperature, but not systemic body temperature...
• Lymphotropic virus may improve noninvasive detection of metastatic prostate cancer (07/11/2008)
  By Karla Gale
  NEW YORK (Reuters Health) - Using an engineered adenoviral vector to mediate reporter gene transfer into prostate cancer cells, sentinal lymph node...
• FISH assay predicts tumor cells' response to chemotherapy (07/10/2008)
  NEW YORK (Reuters Health) - Using fluorescence in situ hybridization (FISH), scientists have identified a "transcription site activation profile" of...
• Preop biomarkers predict prostate cancer relapse (07/10/2008)
  NEW YORK (Reuters Health) - A panel of biomarkers improves the prediction of recurrence of prostate cancer after radical prostatectomy, according to...
• Familial myeloma linked to increased incidence of prostate cancer, MGUS (07/09/2008)
  By Karla Gale
  NEW YORK (Reuters Health) - Researchers have identified a "myeloma-prone family" with five cases of multiple myeloma, five cases of prostate cancer,...
• Chemotherapy wait times not increased by Medicare Modernization Act (07/09/2008)
  NEW YORK (Reuters Health) - Despite concerns, the Medicare Prescription Drug, Improvement, and Modernization Act (MMA) has not adversely affected...
• Demographic variations seen in liver cancer incidence in US (07/09/2008)
  NEW YORK (Reuters Health) - The incidence of hepatocellular carcinoma in the US differs significantly by sex, ethnicity, and age at diagnosis,...
• MDS sues AECL, Canada over reactor cancellation (07/09/2008)
  By Scott Anderson
  TORONTO (Reuters) - MDS Inc said on Wednesday it has filed a C$1.6 billion ($1.58 billion) claim against Atomic Energy of Canada Ltd and the Canadian...
• Lenalidomide active in heavily pretreated leukemia (07/09/2008)
  NEW YORK (Reuters Health) - Lenalidomide can induce complete and partial remissions in patients with relapsed and refractory chronic lymphocytic...
• Lapatinib promising for advanced ErbB2-amplified breast cancer (07/08/2008)
  NEW YORK (Reuters Health) - In a phase II trial, the investigational agent lapatinib was well tolerated and showed clinical activity as first-line...
• Drop in US cancer death rates seen mainly in highly educated individuals (07/08/2008)
  NEW YORK (Reuters Health) - From 1993 to 2001, death rates from common cancers fell in the United States, but this decline was primarily confined to...
• Reducing iron stores by phlebotomy lowers cancer risk in older men (07/08/2008)
  NEW YORK (Reuters Health) - Cancer incidence and mortality in older men may be reduced by repeated phlebotomy to lower serum ferritin levels,...
• Primary androgen deprivation of limited value in localized prostate cancer (07/08/2008)
  NEW YORK (Reuters Health) - In general, primary androgen deprivation therapy (PADT) does not improve the survival of patients with localized prostate...
• CK19 mRNA expression identifies lymph node metastases intraoperatively (07/08/2008)
  NEW YORK (Reuters Health) - Measurement of CK19 mRNA expression intraoperatively can be used as a rapid diagnostic method to detect lymph node...
• Smoking, alcohol among risk factors for vulvar/vaginal carcinoma (07/07/2008)
  NEW YORK (Reuters Health) - Risk factors for invasive squamous cell carcinoma of the vulva and vagina include human papillomavirus (HPV) infection,...
• CHD5 gene suppression tied to poor outcome in neuroblastomas (07/07/2008)
  By David Douglas
  NEW YORK (Reuters Health) - Low CHD5 expression is associated with poorer outcome in patients with neuroblastomas, researchers report in the July 2nd...
• Treatment delays common in men with breast cancer (07/07/2008)
  By Megan Rauscher
  NEW YORK (Reuters Health) - Male breast cancer is often diagnosed at an advanced stage and axillary lymph node involvement is frequently seen at...
• Mantle cell lymphoma on the rise in the US (07/07/2008)
  NEW YORK (Reuters Health) - From 1992 to 2004, the incidence of mantle cell lymphoma (MCL), an aggressive form of non-Hodgkin's lymphoma, increased...
• Survival after radical cystectomy linked to number of lymph nodes removed (07/04/2008)
  By Will Boggs, MD
  NEW YORK (Reuters Health) - More extensive lymphadenectomy is associated with improved survival in patients with lymph node-positive bladder cancer...
• Education reduces children's need for anesthesia during radiotherapy (07/04/2008)
  NEW YORK (Reuters Health) - Among young patients with cancer, a psychoeducational intervention reduces the percentage of patients requiring...
• New program cuts depression in cancer patients (07/03/2008)
  NEW YORK (Reuters Health) - A nurse-delivered intervention can improve depressive symptoms, anxiety, and fatigue in cancer patients with major...
• Anti-thrombosis benefit unclear in cancer patients with catheters (07/03/2008)
  By David Douglas
  NEW YORK (Reuters Health) - Pooled data from randomized trials does not clearly demonstrate a significant advantage for thromboprophylaxis in cancer...
• New device provides real-time assessment of lung cancer status (07/02/2008)
  By Anthony J. Brown, MD
  NEW YORK (Reuters Health) - Using a recently developed device, US researchers have shown that mutations in the epidermal growth factor receptor...
• Heart failure linked to sunitinib treatment (07/02/2008)
  By Michelle Rizzo
  NEW YORK (Reuters Health) - In a study published in the June 1st issue of Cancer, researchers report the development of symptomatic heart failure in...
• Mucosa-restricted antigen induces immunologic response to colorectal cancer (07/01/2008)
  By Will Boggs, MD
  NEW YORK (Reuters Health) - Guanylyl cyclase C (GCC), a protein restricted to the intestinal mucosa, induces an immunotherapeutic response against...
• HER-2 improves survival in patients with breast cancer brain metastasis (07/01/2008)
  By David Douglas
  NEW YORK (Reuters Health) - HER-2 status is a strong predictor of survival in patients with brain metastases from breast cancer, according to...
• Investigational drug combination plus chemotherapy promising in breast cancer cell lines (07/01/2008)
  By Martha Kerr
  NEW YORK (Reuters Health) - A chemotherapy regimen targeting both p53 mutations and tumor vasculature "has complementary and potent antitumor...
• Kaposi's sarcoma remains clinical problem in HIV patients (06/30/2008)
  NEW YORK (Reuters Health) - Despite treatment advances involving highly active antiretroviral therapy (HAART) and chemotherapy, many HIV-infected...
• Metastatic potential may be inherent in DCIS cells (06/30/2008)
  By Martha Kerr
  NEW YORK (Reuters Health) - Ductal carcinoma in situ (DCIS) cells may be able to invade, and perhaps metastasize, from the outset rather than being...
• Molecular breast imaging more cost-effective than MRI without loss of sensitivity (06/30/2008)
  By Martha Kerr
  NEW YORK (Reuters Health) - Research presented at the Department of Defense's annual Era of Hope breast cancer meeting indicates that molecular...
• High birth weight linked to risk of adult-onset rheumatoid arthritis (06/30/2008)
  NEW YORK (Reuters Health) - Infants with higher than average birth weights appear to be twice as likely to develop rheumatoid arthritis (RA) in...
• REFILE: Plasma biomarkers identified in early stage pancreatic cancer (06/30/2008)
  NEW YORK (Reuters Health) - Proteins differentially expressed in a mouse model of pancreatic ductal adenocarcinoma are also present in early-stage...
• Small cell cervical cancer usually has poor prognosis (06/26/2008)
  NEW YORK (Reuters Health) - Small cell carcinoma of the cervix is rare compared to other cervical cancers, but the outlook for patients with this...
• Breast cancer cells traced to transplanted stem cells (06/26/2008)
  By Martha Kerr
  NEW YORK (Reuters Health) - Stem cells can give rise to both breast cancer cells and the cells of the tumor microenvironment. Furthermore, stem...
• EU body warns on anaemia drugs in cancer patients (06/26/2008)
  LONDON (Reuters) - Epoetin, or Epo, drugs should carry a new warning for their use in cancer patients stating that blood transfusion should be the...
• MRI combination best at predicting progression after prostate cancer treatment (06/26/2008)
  NEW YORK (Reuters Health) - Dynamic contrast-enhanced (DCE)-MRI in combination with diffusion-weighted imaging (DWI)-MRI is better than either...
• Outreach program speeds breast cancer diagnosis in black women (06/23/2008)
  By Karla Gale
  NEW YORK (Reuters Health) - Implementation of breast cancer outreach initiatives in Atlanta, Georgia, doubled the proportion of stage 0 tumors...
• African American women face higher death risk from metastatic breast cancer (06/23/2008)
  By Will Boggs, MD
  NEW YORK (Reuters Health) - The higher death risk for African American women with metastatic breast cancer persists in clinical trials where overall...
• HTI-286 shows antitumor activity in prostate cancer (06/23/2008)
  NEW YORK (Reuters Health) - HTI-286, a synthetic analog of the marine sponge product hemiasterlin, is active against prostate cancer in vitro and in...
• PDGF signaling implicated in side effects of stroke therapy (06/23/2008)
  NEW YORK (Reuters Health) - Although tissue plasminogen activator (tPA) can be beneficial for stroke, it can cause hemorrhagic complications and must...

Cardiology

• Sleep disordered breathing common in patients with pulmonary hypertension (07/17/2008)
  NEW YORK (Reuters Health) - Cheyne-Stokes respiration and central sleep apnea are common in patients with pulmonary hypertension, and obstructive...
• Renal transplant ups risk of complications of chronic kidney disease in children (07/17/2008)
  NEW YORK (Reuters Health) - Anemia and hypertension occur more often in children and adolescents with chronic kidney disease (CKD) who have undergone...
• Antihypertensive medication less likely to reduce cardiac hypertrophy in women (07/15/2008)
  NEW YORK (Reuters Health) - Regression of left ventricular hypertrophy (LVH) occurs to a lesser extent in women treated with antihypertensive...
• Prehypertension in young adults linked to coronary calcification in middle age (07/15/2008)
  NEW YORK (Reuters Health) - Low-level elevation of blood pressure during young adulthood is an independent risk factor for atherosclerosis 20 years...
• Integrated intervention improves depression and hypertension (07/14/2008)
  NEW YORK (Reuters Health) - An intervention that integrates treatments for depression and hypertension is better than usual care at improving the...
• Red blood cell fatty acid profile is altered in heart failure patients (07/09/2008)
  By Michelle Rizzo
  NEW YORK (Reuters Health) - Omega- 3 supplementation may not be prudent in patients with left ventricular dysfunction, based on findings published in...
• Bevacizumab shows significant activity in liver cancer (07/09/2008)
  By Martha Kerr
  NEW YORK (Reuters Health) - Bevacizumab, a monoclonal antibody targeting vascular endothelial growth factor (VEGF), may be an option in nonmetastatic...
• Hepatitis C virus infection not directly tied to kidney disease (07/08/2008)
  NEW YORK (Reuters Health) - Infection with hepatitis C virus per se is not associated with an increased risk of developing chronic kidney disease,...
• Cardiomyopathy not improved by intramyocardial skeletal myoblast injections (07/08/2008)
  By Will Boggs, MD
  NEW YORK (Reuters Health) - Intramyocardial injections of skeletal myoblasts in patients with ischemic cardiomyopathy does not improve ventricular...
• Antihypertensive therapy may cut dementia risk in elderly (07/07/2008)
  NEW YORK (Reuters Health) - Although a new study has not shown a significant drop in dementia risk in elderly subjects treated with antihypertensive...
• Aortic stenting improves aortic function in adult coarctation (07/03/2008)
  NEW YORK (Reuters Health) - Aortic stenting improves central aortic function and daytime systolic blood pressure without ameliorating peripheral...
• High normal albuminuria linked to hypertension (07/03/2008)
  NEW YORK (Reuters Health) - Increased albuminuria, even in the upper limits of normal, is associated with an increased risk of incident hypertension,...
• Turner's syndrome boosts risk of pediatric aortic dilation (07/02/2008)
  NEW YORK (Reuters Health) - Girls and young women with Turner's syndrome are at increased risk of aortic dilation, which can lead to aortic...
• Elderly hypertensives with AF at increased risk for cardiac events, death (07/02/2008)
  NEW YORK (Reuters Health) - Elderly hypertensive patients who develop atrial fibrillation (AF), relative to those who maintain normal sinus rhythm,...
• Multitarget therapy best for treatment of severe lupus nephritis (07/02/2008)
  NEW YORK (Reuters Health) - For inducing remission of class V+IV lupus nephritis, multitarget therapy with mycophenolate mofetil, tacrolimus, and...
• Even modest weight gain raises risk of chronic kidney disease (07/01/2008)
  NEW YORK (Reuters Health) - In healthy men of normal weight, relatively small weight gain can adversely affect glomerular filtration rate, an...
• Stroke disparities in US regions may be due in part to diabetes variation (06/27/2008)
  NEW YORK (Reuters Health) - Regional differences in diabetes prevalence may contribute to the geographic disparity in stroke mortality seen in the...
• Brothers of women with PCOS share some of the same metabolic defects (06/27/2008)
  NEW YORK (Reuters Health) - Brothers of women with polycystic ovarian syndrome (PCOS) are likely to exhibit a metabolic phenotype of dyslipidemia and...
• Silent cerebral infarcts apparent on MRI in early middle age (06/26/2008)
  NEW YORK (Reuters Health) - Silent cerebral infarctions - parenchymal lesions detected on MRI in the absence of stroke symptomatology - may be...
• Sudden hearing loss a harbinger of stroke (06/26/2008)
  NEW YORK (Reuters Health) - Sudden sensorineural hearing loss can be an early warning of impending stroke, according to results of a case-control...
• Diabetic ketoacidosis prolongs QT interval in children (06/26/2008)
  By David Douglas
  NEW YORK (Reuters Health) - During diabetic ketoacidosis in children, the QT interval corrected for heart rate (QTc) is often elevated, researchers...
• Angiotensin-converting enzyme inhibitors increase angioedema risk (06/26/2008)
  NEW YORK (Reuters Health) - The risk of angioedema is more than 3 times higher with angiotensin-converting enzyme (ACE) inhibitors than with other...

COPD

• Female gender and smoke exposure predict asthma response to montelukast (07/18/2008)
  NEW YORK (Reuters Health) - In children with asthma treated with inhaled corticosteroids and requiring rescue medication, responsiveness to the...
• Furosemide inhalation can alleviate dyspnea in COPD (07/18/2008)
  NEW YORK (Reuters Health) - Inhalation of furosemide relieves exertional dyspnea in some patients with chronic obstructive pulmonary disease (COPD),...
• Eradicating nasal S. aureus does not improve allergic rhinitis (07/16/2008)
  By David Douglas
  NEW YORK (Reuters Health) - Topical nasal mupirocin is an effective means of eradicating Staphylococcus aureus nasal colonization in patients with...
• Mortality from complicated peptic ulcer high in COPD patients (07/15/2008)
  NEW YORK (Reuters Health) - Chronic obstructive pulmonary disease is associated with substantially increased short-term mortality among patients with...
• Triple therapy superior for treating moderate to severe COPD (07/14/2008)
  By Will Boggs, MD
  NEW YORK (Reuters Health) - Triple therapy with salmeterol/fluticasone and tiotropium is superior to the individual components for patients with...
• Oximetry with capnography defines oxygen therapy needs (07/11/2008)
  NEW YORK (Reuters Health) - Combined oximetry and cutaneous capnography is an effective and non-invasive means of oxygen titration in patients...
• One epinephrine dose may not suffice for children with multiple food allergies (07/09/2008)
  NEW YORK (Reuters Health) - Nearly one in five food-induced anaphylactic reactions that occur in children with multiple food allergies will require...

Dyslipidemia

• Fiber intake may cut preeclampsia risk (07/17/2008)
  NEW YORK (Reuters Health) - With increasing intake of dietary fiber during early pregnancy, the risk of preeclampsia in later pregnancy falls,...
• CORRECTION: Increased carotid distension an independent predictor of coronary events (07/17/2008)
  By Martha Kerr
  NEW YORK (Reuters Health) - B-mode ultrasonography is a simple, noninvasive way to assess carotid distension, which is an independent predictor of...
• Increased carotid distension an independent predictor of coronary events (07/15/2008)
  By Martha Kerr
  NEW YORK (Reuters Health) - B-mode ultrasonography is a simple, noninvasive way to assess carotid distension, which is an independent predictor of...
• Diabetes risk directly related to glucose level, even within normal range (07/11/2008)
  By Anthony J. Brown, MD
  NEW YORK (Reuters Health) - New research suggests that the risk of developing type 2 diabetes is increased with plasma glucose levels well below the...
• Brothers of women with PCOS share some of the same metabolic defects (06/27/2008)
  NEW YORK (Reuters Health) - Brothers of women with polycystic ovarian syndrome (PCOS) are likely to exhibit a metabolic phenotype of dyslipidemia and...

Endometriosis

• Endometriosis drug significantly reduces pain in trial (07/11/2008)
  BANGALORE (Reuters) - Repro Therapeutics Inc. said its lead experimental drug Proflex significantly relieved pain in women suffering from...
• "Better treatment" seen needed for endometriosis (07/04/2008)
  By Megan Rauscher
  NEW YORK (Reuters Health) - Local laparoscopic excision of endometriotic lesions is associated with good short-term outcomes but has a high...

Erectile Dysfunction

• Erectile dysfunction varies with androgen deprivation therapy (07/11/2008)
  NEW YORK (Reuters Health) - A substantial minority of men receiving androgen deprivation therapy for prostate cancer experience erectile dysfunction...

Ethics

• U.S. physicians' group apologizes to black doctors (07/10/2008)
  By Julie Steenhuysen
  CHICAGO (Reuters) - The American Medical Association, the largest physicians' group in the United States, apologized to black doctors on Thursday for...
• Ethics take center stage at fertility conference (07/07/2008)
  By Michael Kahn
  BARCELONA (Reuters) - A U.S. researcher's argument that twins should be the goal of in vitro fertilization drew opposition from many researchers on...

Gastroenterology

• Maintenance with infliximab effective in Crohn's disease (07/18/2008)
  NEW YORK (Reuters Health) - Patients with Crohn's disease who are in remission after treatment with infliximab and immunosuppressives can safely go...
• Liver cancer surgery benefits patients with multiple tumors, portal hypertension (07/16/2008)
  By Will Boggs, MD
  NEW YORK (Reuters Health) - Hepatic resection of hepatocellular carcinoma (HCC) should not be contraindicated in patients with multiple tumors or...
• Oral proton pump inhibitors may be adequate for control of bleeding ulcers (07/14/2008)
  NEW YORK (Reuters Health) - Proton pump inhibitor (PPI) therapy administered by intravenous bolus plus infusion acts only marginally more rapidly...
• Fluvastatin inhibits hepatitis C virus replication (07/07/2008)
  NEW YORK (Reuters Health) - Fluvastatin inhibits hepatitis C virus (HCV) RNA replication in patients with chronic hepatitis C, according to a report...
• Biliary complications more common in living donors of right liver lobe grafts (07/04/2008)
  NEW YORK (Reuters Health) - Living liver donors are significantly more likely to experience biliary complications when donating a right lobe than a...
• Immunological FOBT superior to M2-PK assay as test for colorectal cancer (06/30/2008)
  NEW YORK (Reuters Health) - An office-based immunochemical fecal occult blood test (IFOBT) is significantly more accurate in screening for colorectal...
• Peptide vaccine shows some promise in hard-to-treat HCV (06/30/2008)
  NEW YORK (Reuters Health) - The synthetic peptide vaccine IC41 induces a T-cell response specific to hepatitis C virus (HCV) in patients with chronic...
• Eosinophilic esophagitis prevalent in all age groups (06/30/2008)
  NEW YORK (Reuters Health) - Eosinophilic esophagitis affects people of all ages, though its features are different in children and adults, according...
• High intrahepatic triglyceride content a marker of insulin resistance (06/27/2008)
  By Martha Kerr
  NEW YORK (Reuters Health) - An international team of investigators reports that elevated intrahepatic triglyceride (IHTG) content is inversely...
• Mortality increased in inflammatory bowel disease treated with corticosteroids (06/27/2008)
  NEW YORK (Reuters Health) - The use of corticosteroids in patients with inflammatory bowel disease (IBD) is associated with increased mortality,...
• Hypnosis appears to ease inflammation in ulcerative colitis (06/27/2008)
  NEW YORK (Reuters Health) - Hypnotherapy prompts a reduction in components of the inflammatory response in patients with ulcerative colitis, UK...
• Terlipressin may improve hepatorenal syndrome, but ischemic risks seen (06/23/2008)
  NEW YORK (Reuters Health) - Combination treatment with albumin and the vasopressin analogue terlipressin can improve renal function in patients with...

Genitourinary

• Immunotherapy may boost prostate cancer response to hormone therapy (07/21/2008)
  NEW YORK (Reuters Health) - Patients with nonmetastatic castration-resistant prostate cancer (stage D0.5) treated with an experimental vaccine...
• Limited benefit seen with docetaxel and rapid androgen cycling for prostate cancer (07/17/2008)
  NEW YORK (Reuters Health) - Because of a high incidence of neutropenia and little sustained response, docetaxel with rapid androgen cycling is not...
• Anti-osteoclast monoclonal antibody prevents bone loss in prostate cancer (07/14/2008)
  By Deena Beasley
  LOS ANGELES (Reuters) - In a study, Amgen Inc's experimental drug denosumab reduced the risk of osteoporosis and fracture in men with prostate cancer...
• Elevated C-reactive protein predicts poor outcome in prostate cancer (07/11/2008)
  NEW YORK (Reuters Health) - An elevated plasma C-reactive protein (CRP) concentration is associated with poor survival and a lower probability of...
• Lymphotropic virus may improve noninvasive detection of metastatic prostate cancer (07/11/2008)
  By Karla Gale
  NEW YORK (Reuters Health) - Using an engineered adenoviral vector to mediate reporter gene transfer into prostate cancer cells, sentinal lymph node...
• Endometriosis drug significantly reduces pain in trial (07/11/2008)
  BANGALORE (Reuters) - Repro Therapeutics Inc. said its lead experimental drug Proflex significantly relieved pain in women suffering from...
• Preop biomarkers predict prostate cancer relapse (07/10/2008)
  NEW YORK (Reuters Health) - A panel of biomarkers improves the prediction of recurrence of prostate cancer after radical prostatectomy, according to...
• Familial myeloma linked to increased incidence of prostate cancer, MGUS (07/09/2008)
  By Karla Gale
  NEW YORK (Reuters Health) - Researchers have identified a "myeloma-prone family" with five cases of multiple myeloma, five cases of prostate cancer,...
• Primary androgen deprivation of limited value in localized prostate cancer (07/08/2008)
  NEW YORK (Reuters Health) - In general, primary androgen deprivation therapy (PADT) does not improve the survival of patients with localized prostate...
• Androgen blockade for prostate cancer leads to changes in body composition (07/08/2008)
  By Will Boggs, MD
  NEW YORK (Reuters Health) - Significant changes in muscle, fat and bone mass occur in the months after maximal androgen blockade for prostate cancer,...
• Circulating tumor cell counts predict course of hard-to-treat prostate cancer (07/07/2008)
  By Megan Rauscher
  NEW YORK (Reuters Health) - In patients with castration-resistant prostate cancer, changes in the number of circulating tumor cells are a valuable...
• Abnormal p53 boosts prostate cancer recurrence (06/30/2008)
  By David Douglas
  NEW YORK (Reuters Health) - Prostate cancer is more likely to recur in men with abnormal p53 protein expression compared with their counterparts...
• MRI combination best at predicting progression after prostate cancer treatment (06/26/2008)
  NEW YORK (Reuters Health) - Dynamic contrast-enhanced (DCE)-MRI in combination with diffusion-weighted imaging (DWI)-MRI is better than either...
• HTI-286 shows antitumor activity in prostate cancer (06/23/2008)
  NEW YORK (Reuters Health) - HTI-286, a synthetic analog of the marine sponge product hemiasterlin, is active against prostate cancer in vitro and in...

GERD

• Biological markers needed to gauge second-hand smoke exposure (07/02/2008)
  NEW YORK (Reuters Health) - To best examine the causal relationship between passive smoking and lung cancer, exposure to second-hand smoke (SHS)...

Geriatrics

• Increased homocysteine levels linked to subsequent lacunar infarcts (07/08/2008)
  NEW YORK (Reuters Health) - Total homocysteine in middle-aged women is a risk factor for the occurrence of lacunar infarcts later in life, according...

Hormone Replacement Therapy

• Risk of gallbladder disease lower with transdermal rather than oral HRT (07/10/2008)
  NEW YORK (Reuters Health) - No matter how hormone replacement therapy (HRT) is administered, it appears to increase the risk of gallbladder disease,...
• Osteoporosis increased in scleroderma patients (07/09/2008)
  NEW YORK (Reuters Health) - Patients with scleroderma (systemic sclerosis) have rates of osteoporosis similar to those seen in patients with...
• Suboptimal vitamin D status common in patients with inflammatory bowel disease (07/03/2008)
  By Michelle Rizzo
  NEW YORK (Reuters Health) - Among patients with inflammatory bowel disease, poor vitamin D status correlates with lower bone mineral density,...
• Heel ultrasound may effectively assess osteoporotic fracture risk (07/01/2008)
  By Martha Kerr
  NEW YORK (Reuters Health) - Quantitative heel ultrasound plus the presence of clinical risk factors may provide an easy, effective method of...
• High homocysteine and low vitamin B tied to hip fracture risk (06/27/2008)
  By David Douglas
  NEW YORK (Reuters Health) - Elevated homocysteine is a strong risk factor for osteoporotic fractures in the elderly, and may not simply be a marker...

Hypertension

• Sleep disordered breathing common in patients with pulmonary hypertension (07/17/2008)
  NEW YORK (Reuters Health) - Cheyne-Stokes respiration and central sleep apnea are common in patients with pulmonary hypertension, and obstructive...
• Renal transplant ups risk of complications of chronic kidney disease in children (07/17/2008)
  NEW YORK (Reuters Health) - Anemia and hypertension occur more often in children and adolescents with chronic kidney disease (CKD) who have undergone...
• Fiber intake may cut preeclampsia risk (07/17/2008)
  NEW YORK (Reuters Health) - With increasing intake of dietary fiber during early pregnancy, the risk of preeclampsia in later pregnancy falls,...
• CORRECTION: Increased carotid distension an independent predictor of coronary events (07/17/2008)
  By Martha Kerr
  NEW YORK (Reuters Health) - B-mode ultrasonography is a simple, noninvasive way to assess carotid distension, which is an independent predictor of...
• Increased carotid distension an independent predictor of coronary events (07/15/2008)
  By Martha Kerr
  NEW YORK (Reuters Health) - B-mode ultrasonography is a simple, noninvasive way to assess carotid distension, which is an independent predictor of...
• Antihypertensive medication less likely to reduce cardiac hypertrophy in women (07/15/2008)
  NEW YORK (Reuters Health) - Regression of left ventricular hypertrophy (LVH) occurs to a lesser extent in women treated with antihypertensive...
• Prehypertension in young adults linked to coronary calcification in middle age (07/15/2008)
  NEW YORK (Reuters Health) - Low-level elevation of blood pressure during young adulthood is an independent risk factor for atherosclerosis 20 years...
• Integrated intervention improves depression and hypertension (07/14/2008)
  NEW YORK (Reuters Health) - An intervention that integrates treatments for depression and hypertension is better than usual care at improving the...
• Diabetes risk directly related to glucose level, even within normal range (07/11/2008)
  By Anthony J. Brown, MD
  NEW YORK (Reuters Health) - New research suggests that the risk of developing type 2 diabetes is increased with plasma glucose levels well below the...
• Bevacizumab shows significant activity in liver cancer (07/09/2008)
  By Martha Kerr
  NEW YORK (Reuters Health) - Bevacizumab, a monoclonal antibody targeting vascular endothelial growth factor (VEGF), may be an option in nonmetastatic...
• Hepatitis C virus infection not directly tied to kidney disease (07/08/2008)
  NEW YORK (Reuters Health) - Infection with hepatitis C virus per se is not associated with an increased risk of developing chronic kidney disease,...
• Antihypertensive therapy may cut dementia risk in elderly (07/07/2008)
  NEW YORK (Reuters Health) - Although a new study has not shown a significant drop in dementia risk in elderly subjects treated with antihypertensive...
• New lipid screening guidelines for children released (07/07/2008)
  NEW YORK (Reuters Health) - The American Academy of Pediatrics (AAP) on Monday released new guidelines for lipid screening and treatment in children....
• Exercise ECG identifies cardiac abnormalities in competitive athletes (07/03/2008)
  NEW YORK (Reuters Health) - During medical evaluations of sports participants, exercise electrocardiography (ECG) reveals pathology not identified on...
• Aortic stenting improves aortic function in adult coarctation (07/03/2008)
  NEW YORK (Reuters Health) - Aortic stenting improves central aortic function and daytime systolic blood pressure without ameliorating peripheral...
• High normal albuminuria linked to hypertension (07/03/2008)
  NEW YORK (Reuters Health) - Increased albuminuria, even in the upper limits of normal, is associated with an increased risk of incident hypertension,...
• Turner's syndrome boosts risk of pediatric aortic dilation (07/02/2008)
  NEW YORK (Reuters Health) - Girls and young women with Turner's syndrome are at increased risk of aortic dilation, which can lead to aortic...
• Elderly hypertensives with AF at increased risk for cardiac events, death (07/02/2008)
  NEW YORK (Reuters Health) - Elderly hypertensive patients who develop atrial fibrillation (AF), relative to those who maintain normal sinus rhythm,...
• Multitarget therapy best for treatment of severe lupus nephritis (07/02/2008)
  NEW YORK (Reuters Health) - For inducing remission of class V+IV lupus nephritis, multitarget therapy with mycophenolate mofetil, tacrolimus, and...
• Even modest weight gain raises risk of chronic kidney disease (07/01/2008)
  NEW YORK (Reuters Health) - In healthy men of normal weight, relatively small weight gain can adversely affect glomerular filtration rate, an...
• Excellent results with early, aggressive treatment in RA (06/30/2008)
  By Martha Kerr
  NEW YORK (Reuters Health) - Continuous methotrexate and intra-articular corticosteroids can achieve "excellent clinical response and disease control...
• Stroke disparities in US regions may be due in part to diabetes variation (06/27/2008)
  NEW YORK (Reuters Health) - Regional differences in diabetes prevalence may contribute to the geographic disparity in stroke mortality seen in the...
• Brothers of women with PCOS share some of the same metabolic defects (06/27/2008)
  NEW YORK (Reuters Health) - Brothers of women with polycystic ovarian syndrome (PCOS) are likely to exhibit a metabolic phenotype of dyslipidemia and...
• Silent cerebral infarcts apparent on MRI in early middle age (06/26/2008)
  NEW YORK (Reuters Health) - Silent cerebral infarctions - parenchymal lesions detected on MRI in the absence of stroke symptomatology - may be...
• Sudden hearing loss a harbinger of stroke (06/26/2008)
  NEW YORK (Reuters Health) - Sudden sensorineural hearing loss can be an early warning of impending stroke, according to results of a case-control...
• Angiotensin-converting enzyme inhibitors increase angioedema risk (06/26/2008)
  NEW YORK (Reuters Health) - The risk of angioedema is more than 3 times higher with angiotensin-converting enzyme (ACE) inhibitors than with other...

Immunology

• Most children with cow's milk allergy can tolerate heated milk (07/21/2008)
  NEW YORK (Reuters Health) - Seventy-five percent of children with milk allergy will tolerate extensively heated milk, according to a report in the...
• Female gender and smoke exposure predict asthma response to montelukast (07/18/2008)
  NEW YORK (Reuters Health) - In children with asthma treated with inhaled corticosteroids and requiring rescue medication, responsiveness to the...
• Regular salmeterol use for asthma ups risk of serious adverse events (07/17/2008)
  NEW YORK (Reuters Health) - Patients with chronic asthma who use the long-acting beta-2 agonist salmeterol on a daily basis are at increased risk for...
• U.S. still flunks healthcare test, group says (07/17/2008)
  By Maggie Fox, Health and Science Editor
  WASHINGTON (Reuters) - The United States fails on most measures of health care quality, with Americans waiting longer to see doctors and more likely...
• Adding etanercept to methotrexate ups remission odds in rheumatoid arthritis (07/15/2008)
  NEW YORK (Reuters Health) - Compared with methotrexate monotherapy, combined treatment with methotrexate and etanercept is associated with higher...
• Etanercept improves outcomes somewhat in corticosteroid-refractory asthma (07/15/2008)
  NEW YORK (Reuters Health) - Tumor necrosis factor (TNF) blockade with etanercept produces a small improvement in asthma control and systemic...
• Rituximab diminishes flu vaccine response in RA patients (07/14/2008)
  NEW YORK (Reuters Health) - Use of rituximab in rheumatoid arthritis (RA) patients is associated with a significant reduction in response to...
• Abnormal body fat distribution despite seen in women with RA (07/11/2008)
  NEW YORK (Reuters Health) - Women with rheumatoid arthritis (RA) have an increased odds of having abnormal body fat distribution, sarcopenia and...
• Rheumatoid factor modulates excess mortality in rheumatoid arthritis (07/10/2008)
  NEW YORK (Reuters Health) - The mortality gap between patients with rheumatoid arthritis and the general population is limited to those with...
• One epinephrine dose may not suffice for children with multiple food allergies (07/09/2008)
  NEW YORK (Reuters Health) - Nearly one in five food-induced anaphylactic reactions that occur in children with multiple food allergies will require...
• TNF-alpha assay shows cytokine response to methotrexate in RA patients (07/02/2008)
  NEW YORK (Reuters Health) - An investigational in vitro tumor necrosis factor (TNF)-alpha assay may be useful in predicting treatment response in...
• Excellent results with early, aggressive treatment in RA (06/30/2008)
  By Martha Kerr
  NEW YORK (Reuters Health) - Continuous methotrexate and intra-articular corticosteroids can achieve "excellent clinical response and disease control...
• High birth weight linked to risk of adult-onset rheumatoid arthritis (06/30/2008)
  NEW YORK (Reuters Health) - Infants with higher than average birth weights appear to be twice as likely to develop rheumatoid arthritis (RA) in...
• Inflammatory processes may link asthma and rhinosinusitis (06/26/2008)
  NEW YORK (Reuters Health) - A study in asthmatic patients published in the June issue of Mayo Clinic Proceedings suggests a direct relationship among...

Infectious Disease

• Levofloxacin effective for acute otitis media in infants and young children (07/11/2008)
  By Will Boggs, MD
  NEW YORK (Reuters Health) - Levofloxacin is as effective as amoxicillin/clavulanate for treating infants and young children with recurrent or...
• High-risk HPV DNA detected in human breast milk (07/04/2008)
  By Karla Gale
  NEW YORK (Reuters Health) - Human papillomavirus-16 (HPV-16) DNA can be detected in human breast milk collected during the early postpartum period,...
• MRSA flourishes in overcrowded, understaffed hospitals (06/23/2008)
  NEW YORK (Reuters Health) - Emphasis on increased efficiency and cost-cutting has led to widespread hospital overcrowding and understaffing, an...

Lung Cancer

• Gene expression profiles with clinical data prognostic for early stage lung cancer (07/21/2008)
  By Karla Gale
  NEW YORK (Reuters Health) - Gene expression signatures predict survival in patients with early stage lung cancer, particularly when combined with...
• Zoledronic acid reduces fracture risk in cancer patients with bone metastases (07/18/2008)
  NEW YORK (Reuters Health) - The bisphosphonate zoledronic acid normalizes or maintains N-telopeptide of type 1 collagen (NTx) levels in cancer...
• Chemotherapy wait times not increased by Medicare Modernization Act (07/09/2008)
  NEW YORK (Reuters Health) - Despite concerns, the Medicare Prescription Drug, Improvement, and Modernization Act (MMA) has not adversely affected...
• Drop in US cancer death rates seen mainly in highly educated individuals (07/08/2008)
  NEW YORK (Reuters Health) - From 1993 to 2001, death rates from common cancers fell in the United States, but this decline was primarily confined to...
• New device provides real-time assessment of lung cancer status (07/02/2008)
  By Anthony J. Brown, MD
  NEW YORK (Reuters Health) - Using a recently developed device, US researchers have shown that mutations in the epidermal growth factor receptor...
• Biological markers needed to gauge second-hand smoke exposure (07/02/2008)
  NEW YORK (Reuters Health) - To best examine the causal relationship between passive smoking and lung cancer, exposure to second-hand smoke (SHS)...

Metabolic Disorders

• Fiber intake may cut preeclampsia risk (07/17/2008)
  NEW YORK (Reuters Health) - With increasing intake of dietary fiber during early pregnancy, the risk of preeclampsia in later pregnancy falls,...
• CORRECTION: Increased carotid distension an independent predictor of coronary events (07/17/2008)
  By Martha Kerr
  NEW YORK (Reuters Health) - B-mode ultrasonography is a simple, noninvasive way to assess carotid distension, which is an independent predictor of...
• Increased carotid distension an independent predictor of coronary events (07/15/2008)
  By Martha Kerr
  NEW YORK (Reuters Health) - B-mode ultrasonography is a simple, noninvasive way to assess carotid distension, which is an independent predictor of...
• Diabetes risk directly related to glucose level, even within normal range (07/11/2008)
  By Anthony J. Brown, MD
  NEW YORK (Reuters Health) - New research suggests that the risk of developing type 2 diabetes is increased with plasma glucose levels well below the...

Migraine

• Prophylactic botulinum type A an option in some migraine patients (07/11/2008)
  NEW YORK (Reuters Health) - Botulinum toxin type A (BoNTA) may be a useful prophylactic agent in patients with frequent migraines that are poorly...
• Sumatriptan-naproxen combination effective early treatment for migraine (07/08/2008)
  NEW YORK (Reuters Health) - Early treatment with sumatriptan plus naproxen for acute migraine provides effective relief of pain and other symptoms...
• Exercise does not appear to be efficacious in migraine therapy (07/01/2008)
  NEW YORK (Reuters Health) - Exercise therapy does not appear to reduce headache attack or duration in migraine patients, according to findings...

Neurology

• Topiramate linked to birth defects (07/21/2008)
  NEW YORK (Reuters Health) - The antiepileptic drug topiramate (Topamax) has been linked with an increased risk of major congenital malformations when...
• Phenytoin clearance unaltered in elderly epileptics (07/18/2008)
  By David Douglas
  NEW YORK (Reuters Health) - In elderly patients with epilepsy, phenytoin half-life and clearance during maintenance therapy does not appear to differ...
• No persisting benefit seen with repeated botulinum toxin for cerebral palsy (07/16/2008)
  NEW YORK (Reuters Health) - As a treatment for leg spasticity in cerebral palsy, injections of botulinum toxin A provide temporary relief but...
• Warfarin may be safer without heparin bridging after cardioembolic stroke (07/15/2008)
  NEW YORK (Reuters Health) - Early anticoagulation following cardioembolic stroke appears to halt stroke progression, according to a retrospective...
• Higher MMSE cutpoint identifies cognitive problems in highly educated adults (07/14/2008)
  By Karla Gale
  NEW YORK (Reuters Health) - The traditional cutpoint on the Mini-Mental State Examination (MMSE) score for classifying older adults as cognitively...
• Cardiorespiratory fitness linked to less brain atrophy in early Alzheimer's disease (07/14/2008)
  By Karla Gale
  NEW YORK (Reuters Health) - Higher levels of physical fitness may preserve brain volume in the early clinical stages of Alzheimer's disease, new...
• Prophylactic botulinum type A an option in some migraine patients (07/11/2008)
  NEW YORK (Reuters Health) - Botulinum toxin type A (BoNTA) may be a useful prophylactic agent in patients with frequent migraines that are poorly...
• Pfizer says its epilepsy drugs need no warning (07/10/2008)
  By Susan Heavey
  BELTSVILLE, Md. (Reuters) - Pfizer Inc said its epilepsy drugs do not increase the risk of suicidal behavior and should be exempt from tougher...
• Electromyography detects voluntary movement in disorders of consciousness (07/09/2008)
  By Will Boggs, MD
  NEW YORK (Reuters Health) - Electromyography (EMG) can provide an objective indication of awareness in patients with disorders of consciousness by...
• Sumatriptan-naproxen combination effective early treatment for migraine (07/08/2008)
  NEW YORK (Reuters Health) - Early treatment with sumatriptan plus naproxen for acute migraine provides effective relief of pain and other symptoms...
• Group therapy helpful in restless legs syndrome (07/07/2008)
  NEW YORK (Reuters Health) - Cognitive behavioral group therapy improves patients' ability to cope with restless legs syndrome, German researchers...
• Role of PINK1 gene mutations in Parkinson disease elucidated (07/04/2008)
  NEW YORK (Reuters Health) - Research suggests that homozygous PINK1 mutations may manifest in an early-onset autosomal recessive form of Parkinson...
• Exercise does not appear to be efficacious in migraine therapy (07/01/2008)
  NEW YORK (Reuters Health) - Exercise therapy does not appear to reduce headache attack or duration in migraine patients, according to findings...
• Horizontal head impulse test helps spot stroke (06/27/2008)
  By David Douglas
  NEW YORK (Reuters Health) - The horizontal head impulse test (h-HIT) is useful in differentiating acute cerebellar strokes from vestibular neuritis,...
• Increased hemorrhagic stroke risk attenuates atorvastatin benefits (06/26/2008)
  By Will Boggs, MD
  NEW YORK (Reuters Health) - In the Stroke Prevention by Aggressive Reduction in Cholesterol Levels (SPARCL) trial, statins were reportedly associated...
• Plasma amyloid-beta protein, CRP influence Alzheimer's progression (06/23/2008)
  By Megan Rauscher
  NEW YORK (Reuters Health) - Patients with Alzheimer's disease (AD) who have low blood levels of amyloid-beta protein and C-reactive protein may...
• Capsaicin patch relieves painful HIV-associated neuropathy (06/23/2008)
  NEW YORK (Reuters Health) - In a double-blind randomized study, a single application of a high-concentration capsaicin skin patch (NGX-4010) produced...

Nutrition

• Adolescents, an underserved group, have low immunization rates (07/21/2008)
  By Martha Kerr
  NEW YORK (Reuters Health) - Many adolescents do not receive recommended immunizations, the National Vaccine Advisory Committee (NVAC) reports. In...
• Early nutrition saves lives of patients with severe brain injury (07/21/2008)
  NEW YORK (Reuters Health) - Adequate nutrition within the first few days after severe traumatic brain injury (TBI) improves survival, according to...
• Maternal diabetes linked to early-onset diabetes in offspring (07/18/2008)
  NEW YORK (Reuters Health) - Intrauterine exposure to maternal diabetes and obesity raises the risk of type 2 diabetes in adolescents, according to...
• More Americans obese, government finds (07/17/2008)
  WASHINGTON (Reuters) - More than a quarter of all Americans are now obese, the latest U.S. government figures show.
• Routine tests may underestimate kidney disease prevalence in HIV (07/15/2008)
  NEW YORK (Reuters Health) - Serum creatinine-based estimates of glomerular filtration rates (GFR) may overestimate the true GFR in patients with HIV...
• Primary amenorrhea and PCOS tied to metabolic syndrome (07/10/2008)
  By David Douglas
  NEW YORK (Reuters Health) - Young women with primary amenorrhea as a manifestation of polycystic ovarian syndrome (PCOS) appear to be at increased...
• Ventricular mass tied to metabolic syndrome independent of blood pressure (07/09/2008)
  By David Douglas
  NEW YORK (Reuters Health) - Left ventricular mass and relative wall thickness are increased in patients with the metabolic syndrome and are related...
• New lipid screening guidelines for children released (07/07/2008)
  NEW YORK (Reuters Health) - The American Academy of Pediatrics (AAP) on Monday released new guidelines for lipid screening and treatment in children....
• SGA children may develop visceral adiposity without being overweight (07/04/2008)
  NEW YORK (Reuters Health) - Children born small for gestational age (SGA) are prone to develop visceral adiposity, sometimes without being...
• Obesity may protect against cardiac events after multi-vessel stenting (07/02/2008)
  NEW YORK (Reuters Health) - The results of the Arterial Revascularization Therapies Study Part II (ARTS II) show that body mass index (BMI) "had no...
• Fatty liver disease in obese children strongly associated with metabolic syndrome (06/30/2008)
  NEW YORK (Reuters Health) - Nonalcoholic fatty liver disease in over-weight or obese children appears to be a risk factor for the metabolic syndrome,...

Obesity

• Adolescents, an underserved group, have low immunization rates (07/21/2008)
  By Martha Kerr
  NEW YORK (Reuters Health) - Many adolescents do not receive recommended immunizations, the National Vaccine Advisory Committee (NVAC) reports. In...
• Maternal diabetes linked to early-onset diabetes in offspring (07/18/2008)
  NEW YORK (Reuters Health) - Intrauterine exposure to maternal diabetes and obesity raises the risk of type 2 diabetes in adolescents, according to...
• More Americans obese, government finds (07/17/2008)
  WASHINGTON (Reuters) - More than a quarter of all Americans are now obese, the latest U.S. government figures show.
• Abnormal body fat distribution despite seen in women with RA (07/11/2008)
  NEW YORK (Reuters Health) - Women with rheumatoid arthritis (RA) have an increased odds of having abnormal body fat distribution, sarcopenia and...
• Ventricular mass tied to metabolic syndrome independent of blood pressure (07/09/2008)
  By David Douglas
  NEW YORK (Reuters Health) - Left ventricular mass and relative wall thickness are increased in patients with the metabolic syndrome and are related...
• SGA children may develop visceral adiposity without being overweight (07/04/2008)
  NEW YORK (Reuters Health) - Children born small for gestational age (SGA) are prone to develop visceral adiposity, sometimes without being...
• Obesity may protect against cardiac events after multi-vessel stenting (07/02/2008)
  NEW YORK (Reuters Health) - The results of the Arterial Revascularization Therapies Study Part II (ARTS II) show that body mass index (BMI) "had no...
• Even modest weight gain raises risk of chronic kidney disease (07/01/2008)
  NEW YORK (Reuters Health) - In healthy men of normal weight, relatively small weight gain can adversely affect glomerular filtration rate, an...
• Fatty liver disease in obese children strongly associated with metabolic syndrome (06/30/2008)
  NEW YORK (Reuters Health) - Nonalcoholic fatty liver disease in over-weight or obese children appears to be a risk factor for the metabolic syndrome,...

Osteoarthritis

• Joint replacement results often excellent long-term in elderly patients (07/14/2008)
  NEW YORK (Reuters Health) - Although it may take several weeks for elderly patients to recover from joint replacement surgery, excellent long-term...
• Combination drug appears useful for hand osteoarthritis (07/04/2008)
  NEW YORK (Reuters Health) - The synergistic drug candidate CRx-102, which combines dipyridamole with low dose prednisolone, is a safe and effective...

Osteoporosis

• Anti-osteoclast monoclonal antibody prevents bone loss in prostate cancer (07/14/2008)
  By Deena Beasley
  LOS ANGELES (Reuters) - In a study, Amgen Inc's experimental drug denosumab reduced the risk of osteoporosis and fracture in men with prostate cancer...
• Osteoporosis increased in scleroderma patients (07/09/2008)
  NEW YORK (Reuters Health) - Patients with scleroderma (systemic sclerosis) have rates of osteoporosis similar to those seen in patients with...