There has been great confusion in field of lipid management as to whether or not LDL targets should be used to guide therapy in patients with hypercholesterolemia. In this Clinical Coffee Break, Dr. Christopher Cannon, professor of medicine at Harvard Medical School, will discuss why providers should consider using LDL targets to guide lipid management. He will review new evidence in support of using specific LDL targets for patients at low-, moderate- and high-cardiovascular risk. Additionally, he will discuss how to identify patients who are not achieving LDL-C control and who may be candidates for PCSK9 inhibitor therapy.
In this case presentation, Dr. Gluckman discusses a patient with hypercholesterolemia and reviews a step-wise, evidence-based strategy for incorporating non-statin therapy, such as PCSK9 inhibitors, for lowering low-density lipoprotein (LDL)-cholesterol.