Whether you prefer to learn via quick-hitting video-based activities featuring a dialogue between 2 expert faculty or by working through an in-depth, branching patient case, these complimentary activities can help you improve the care of your patients with major depressive disorder (MDD) who are suffering from an incomplete treatment response. Choose the format that best meets your learning style or reinforce your knowledge and earn a maximum of 2 CME/CE credits by engaging in all 4 activities.

Learning Objectives

  1. Discuss the benefits of early intervention for patients with major depressive disorder (MDD) who have not responded fully to treatment
  2. Identify patients with a partial response to therapy so that prompt treatment advancement can be implemented
  3. Examine strategies to advance pharmacotherapy, including adjunctive therapy with a second-generation antipsychotic
  4. Formulate individualized plans for treatment advancement in patients with MDD experiencing a partial response to monotherapy


Pamela Kushner, MD, FAAFP

Clinical Professor
Director, Kushner Wellness
UC Irvine Medical Center
Orange, CA

Jeffrey Rado, MD, MPH, FAPA

Associate Professor
Northwestern University Feinberg School of Medicine
Chicago, IL

Marlene Freeman

Professor of Psychiatry, Harvard Medical School
Associate Director, Ammon-Pinizzotto Center for Women’s Mental Health
Medical Director, Clinical Trials Network and Institute
Massachusetts General Hospital
Boston, MA

Commercial Supporters

Supported by an educational grant from Otsuka America Pharmaceutical, Inc. and Lundbeck

Education Partners

Pri-Med Institute

Mental Health America, Inc.

Fine Print

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The opinions, ideas, and recommendations expressed in this educational activity are those of the faculty only and are not necessarily endorsed, nor do they necessarily reflect, those of their affiliated institutions, Pri-Med Institute, Pri-Med Institute Advisory Boards and Consultants, or DBC Pri-Med, LLC.

Clinical judgment must guide each clinician in weighing the possible risks, benefits, or contraindications of any diagnostics, interventions or treatments discussed. Clinicians should review manufacturers’ product information and consider these with the recommendations of other authorities when applying the assessment and/or clinical management strategies discussed in this activity to the care of their patients.

Pri-Med Institute Accredited Provider
Pri-Med programs are owned and operated by DBC Pri-Med, LLC, a division of Diversified Communications, Inc. Pri-Med Institute, the accredited division of Pri-Med, is accredited with commendation by the ACCME and approved as a provider of continuing education by the AANP. Pri-Med Institute is the accredited provider for this activity.

Disclosures and Conflict of Interest
Pri-Med Institute requires all individuals in a position to influence educational content for Pri-Med Institute-certified CME activities to disclose relevant personal financial relationships with commercial interests prior to contributing to its educational activities. Pri-Med Institute assesses disclosed relationships and follows a defined process to resolve real or implied conflicts to ensure, to the best of its ability, that all educational content is free of commercial bias. Financial disclosures are listed in the activity syllabus and will also be printed on the slides and announced at the start of each presentation. Pri-Med Institute and Vindico Medical Education staff have no relevant financial relationships to disclose.

Discussion of Off-Label Uses and Investigational Products
During the course of their presentations, the faculty may mention uses of products that have not been approved in the United States for the indication(s) being discussed. All presenters are instructed to notify participants when they are discussing unapproved uses or investigational agents. In addition, specific slides will include notation of the off-label use or investigational agent being discussed. Views presented related to unapproved uses of products are solely those of the presenter(s) and are not endorsed by Pri-Med Institute or DBC Pri-Med, LLC.

Questions? If you have questions about this activity, please email or call (877) 477-4633.

Pri-Med Institute educational activities are developed and conducted in accordance with the ACCME's Essential Areas and Policies. It is the mission of Pri-Med Institute to develop and present educational activities that are timely, fair-balanced, scientifically rigorous, and that serve to improve patient outcomes. To that end, we welcome your comments about how to better serve your needs.