Understanding Tolerance, Physical Dependence, and Addiction
The most appropriate analgesic regimen for some patients may include the use of opioids as a component of pain management. Opioids may be considered for pain severe enough to require an opioid when alternative treatments are inadequate and when the benefits of opioids are expected to outweigh the risks. Before prescribing opioids, it is essential for clinicians to screen patients for risk of opioid-related aberrant behaviors using validated tools. It is also essential to differentiate among opioid tolerance, physical dependence, and addiction, and as to how these conditions may present clinically.
This activity is supported by an independent educational grant from the Opioid Analgesic REMS Program Companies. Please see https://ce.opioidanalgesicrems.com/RpcCEUI/rems/pdf/resources/List_of_RPC_Companies.pdf for a listing of REMS Program Companies. This activity is intended to be fully compliant with the Opioid Analgesic REMS education requirements issued by the U.S. Food and Drug Administration (FDA).
Professor of Anesthesiology and Medicine
The Jacobs School of Medicine and Biomedical Sciences at the University at Buffalo
Chief, Pain Medicine and Professor of Oncology
Roswell Park Cancer Institute
The following relevant financial relationships have been disclosed by faculty, and all have been mitigated by Pri-Med Institute.
Oscar A. de Leon-Casasola, MD: Advisory Board for Esteve Pharma, Heron Therapeutics, Medtronic, Tremeau Pharma.
Katherine E. Galluzzi, DO, CMD, FACOFP: No relevant financial relationships to disclose.
Non-faculty contributors and others involved in the planning, development, and editing/review of the content have no relevant financial relationships to disclose.
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Opioid Analgesic REMS Program Companies
Miller Medical Communications, LLC
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