Managing Patients with Overlapping Cardiovascular, Kidney, and Metabolic Diseases: Practical Insights for Primary Care Teams

Overview

Cardiovascular-kidney-metabolic (CKM) syndrome presents significant diagnostic and management challenges across primary, specialty, and integrated care settings, where patients with heterogeneous clinical presentations and overlapping comorbidities —including heart failure, chronic kidney disease, diabetes, and obesity—often require complex clinical decision-making in time-constrained ambulatory care environments. This program defines CKM syndrome and its clinical significance while reviewing evidence-based screening and staging approaches, emerging therapeutic options, and coordinated, patient-centered management strategies.