Dr. Darren K. McGuire, MD, MHSc is Distinguished Teaching Professor of Medicine at University of Texas Southwestern Medical Center in the Division of Cardiology, where he holds the Dallas Heart Ball Chair for Research on Heart Disease in Women. Dr. McGuire is the Lead Physician of the Parkland Hospital and Health System Cardiology clinics. Dr. McGuire’s expertise is in large scale CV Outcomes clinical trial design and execution, and drug registration/regulation, with a focus in the area of diabetes and cardiovascular disease. He presently has leadership roles for numerous international cardiovascular clinical outcomes trials, including T2DM, obesity, and lipid trials. Dr. McGuire is a previous member of the FDA Cardiovascular and Renal Drugs Advisory Committee and remains an FDA ad hoc consultant. He is Deputy Editor of Circulation, Senior Editor of Diabetes and Vascular Disease Research and co-editor of the textbook: Diabetes in Cardiovascular Disease: A Companion to Braunwald’s Heart Disease. Dr. McGuire has authored/co-authored over 300 peer-reviewed manuscripts, reviews, editorials and book chapters.