Dr. Pradhan is an epidemiologist and cardiologist actively involved in the design, conduct, and analysis of a number of large-scale randomized clinical trials and observational studies of cardiovascular disease, peripheral artery disease (PAD), and type 2 diabetes (T2D). She holds joint appointments at the Brigham and Women’s Hospital (BWH), Harvard Medical School (HMS) and VA Boston Medical Center (VAMC). She has served as the principal investigator of the LANCET trial (a randomized clinical trial of insulin glargine for CRP reduction in early T2D) and several NIH R01s evaluating biomarkers of statin-induced diabetes in the JUPITER trial, evaluating the treatment effects of randomized vitamin D and omega-3 fatty acid supplementation on T2D incidence in the VITAL trial, and evaluating the effect of randomized anti-inflammatory therapy with low dose methotrexate on PAD incidence within the Cardiovascular Inflammation Reduction Trial (CIRT). She also serves as Scientific Director of the Preventive Medicine Cohorts Biorepository (BWH). In addition to her research activities, she actively participates in teaching and mentoring of students and trainees within the Division of Preventive Medicine at the Brigham and Women’s Hospital, Harvard Medical School, and is a clinical cardiologist and echocardiographer at the VA Boston Medical Center.