Cases from Liverland: Making Sense of LFTs and MASLD

MASLD is the dominant chronic liver disease worldwide. In this talk, Dr. Chopra will address the epidemiology, clinical features, and ways to address the severity of the liver disease in patients with MASLD. Weight loss remains the cornerstone of treatment, and GLP-1 agonists are clearly game changers. He will also address the most common causes of elevated liver enzymes.

CME/CE Information

1.00 AMA PRA Category 1 Credits™ or 1.00 AANP, including 0.20 AANP Pharm

Release Date: 10/8/2026

Expiration Date: 11/29/2026

Topics

Faculty

Sanjiv Chopra, MD, MACP, FRCP (London)

Learning Objectives

Describe the epidemiology and clinical features of MASLD
Review laboratory tests, FIB-4 scores, and the use of the FibroScan in assessing the severity of MASLD
Discuss treatment options for MASLD, and mention the potential use of vitamin D3 and coffee consumption in addressing hepatic fibrosis in these patients
Develop a working knowledge of the most prevalent causes of elevated liver enzymes
Explain how isolated elevations in ALT and AST can be due to non-hepatic origin

Faculty

Sanjiv Chopra, MD, MACP, FRCP (London)

Professor of Medicine, Harvard Medical School, Boston, MA

Marshall Wolf Master Clinician Educator, Brigham and Women's Hospital, Boston, Massachusetts

Editor In Chief of the Hepatology Section for Up To Date

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Disclosures

All individuals in control of content for this activity (including faculty, moderator, editors, reviewers) have disclosed no relevant financial relationships.

CME/CE Information

AMA PRA Category 1 Credits™

Accreditation Statement

Pri-Med Institute is accredited by the Accreditation Council for Continuing Medical Education (ACCME) to provide continuing medical education for physicians.

Designation Statement

Pri-Med Institute designates this enduring material for a maximum of 1.00 AMA PRA Category 1 Credit™. Physicians should claim only the credit commensurate with the extent of their participation in the activity.

AANP

Accreditation Statement

Pri-Med Institute is accredited by the American Association of Nurse Practitioners^® as an approved provider of nurse practitioner continuing education. Provider number: 040308.

Designation Statement

This activity is approved for 1.00 contact hour (which includes 0.20 hour of pharmacology).

Fine Print

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Clinical judgment must guide each clinician in weighing the possible risks, benefits, or contraindications of any diagnostics, interventions or treatments discussed. Clinicians should review manufacturers’ product information and consider these with the recommendations of other authorities when applying the assessment and/or clinical management strategies discussed in this activity to the care of their patients.

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Discussion of Off-Label Uses and Investigational Products
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