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When patients with T2DM have difficulty controlling their glucose with standard approaches, or are newly diagnosed but severely hyperglycemic, insulin is commonly used to help control their metabolism. Using long acting, once a day agents is a standard of care but in the last 15 years, the costs of insulin has skyrocketed. During this episode we will review a study examining the effects of using Neutral Protamine Hagedorn Insulin (NPH) rather than once a day insulin on A1c control and risk for hypoglycemia and discuss their findings, which suggest NPH can be used with equivalent glycemic control and with no additional risk.

We will discuss the use of azithromycin as a therapeutic option for patients with persistent symptomatic asthma despite controller maintenance therapy with inhaled corticosteroids and a long-acting bronchodilator.

What do you say when your 50-year-old patient that has been relatively sedentary in the last 3 decades wants to do a triathlon? In this episode, we will review a U.S. case series of participants in triathlon races from 1985-2016, and discuss risk, reward, and reality.

If you become frustrated trying to get a thigh cuff onto the arm of an obese patient, we may have the answer.


Join us as we discuss decision aids used to assess contraceptive knowledge and intentions that can be easily incorporated in primary care practice.

In this session we discuss the first EB guidelines by the AAP on body modification, piercing and scarification, including complications and assessment of risk


Since their arrival, oral anti-fungal agents have been thought to induce liver disease. Often, these medications are avoided or used with caution and frequent laboratory testing. Join us in a discussion of a recent study that builds on previous work showing the risk of using these agents is extremely small.

How much exercise makes a difference in the primary prevention of depression and anxiety? Find out in this podcast which will provide insights from Norway’s HUNT cohort study that followed a healthy cohort of 33,908 individuals for 11 years.


This podcast reviews a recent study evaluating the benefit of adding a weighted vest to dietary interventions to promote weight loss and discusses its implications for clinical practice.

For patients with acute stroke without baseline hypoxia, supplemental oxygen has potential benefits but also potential harms. We will review the latest data from a large randomized trial.


According to the latest data, 1 in 7 US women experience perinatal depression, described as depression occurring during pregnancy and up to one year after childbirth. There is compelling evidence that perinatal depression can have short and long-term effects on both women and their children. The USPSTF has published new recommendations encouraging clinicians to screen pregnant and postpartum persons for depression and provide those who are at increased risk of perinatal depression with counseling interventions. (Grade B recommendation).

Systematic Review data has found the risk of adverse events, including MI, Stroke, CV mortality and all cause mortality are increased when SU are used