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Overview

This keynote presentation will explore the difference between chronological age and biological age, and why biological aging is the strongest risk factor for most adult diseases. Participants will learn how the Human Longevity Laboratory (HLL) uses a comprehensive, multidimensional approach to measure biological age through molecular profiling, physiologic testing, imaging, and AI-based tools across multiple organ systems. The session will highlight why aging must be assessed in multiple dimensions to accurately understand human healthspan and disease vulnerability. Finally, the presentation will discuss the vision for the Global Human Healthspan Interventions Testing Network and its mission to rigorously evaluate interventions designed to extend human healthspan.

Learning Objectives

  • Differentiate chronological age from biological age and describe their relevance to disease risk
  • Describe key approaches used to measure biological age in humans
  • Explain the importance of multidimensional assessment of aging across organ systems